[][] mmu Nfatc1 Gene 
functional annotation
Function   nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
GO BP
GO:0060854 [list] [network] branching involved in lymph vessel morphogenesis  (2 genes)  IMP  
GO:0002337 [list] [network] B-1a B cell differentiation  (3 genes)  IMP  
GO:0044838 [list] [network] cell quiescence  (5 genes)  IMP  
GO:0003180 [list] [network] aortic valve morphogenesis  (6 genes)  IMP  
GO:2000647 [list] [network] negative regulation of stem cell proliferation  (6 genes)  IMP  
GO:0003179 [list] [network] heart valve morphogenesis  (7 genes)  IMP  
GO:0042634 [list] [network] regulation of hair cycle  (7 genes)  IMP  
GO:0061384 [list] [network] heart trabecula morphogenesis  (8 genes)  IMP  
GO:0014883 [list] [network] transition between fast and slow fiber  (9 genes)  IMP  
GO:0033173 [list] [network] calcineurin-NFAT signaling cascade  (10 genes)  IMP ISO  
GO:0003184 [list] [network] pulmonary valve morphogenesis  (11 genes)  IMP  
GO:0001946 [list] [network] lymphangiogenesis  (14 genes)  IGI  
GO:0030316 [list] [network] osteoclast differentiation  (20 genes)  IGI  
GO:0001837 [list] [network] epithelial to mesenchymal transition  (31 genes)  IMP  
GO:0060412 [list] [network] ventricular septum morphogenesis  (37 genes)  IMP  
GO:0045668 [list] [network] negative regulation of osteoblast differentiation  (49 genes)  IDA  
GO:0000082 [list] [network] G1/S transition of mitotic cell cycle  (62 genes)  IMP  
GO:0006816 [list] [network] calcium ion transport  (141 genes)  IMP  
GO:0007507 [list] [network] heart development  (222 genes)  IMP  
GO:0006357 [list] [network] regulation of transcription by RNA polymerase II  (382 genes)  IMP  
GO:0035556 [list] [network] intracellular signal transduction  (394 genes)  ISO  
GO:0010628 [list] [network] positive regulation of gene expression  (404 genes)  IDA  
GO:0045893 [list] [network] positive regulation of transcription, DNA-templated  (536 genes)  ISO  
GO:0000122 [list] [network] negative regulation of transcription by RNA polymerase II  (754 genes)  IDA IGI IMP  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (1047 genes)  IDA ISO  
GO:0006351 [list] [network] transcription, DNA-templated  (1853 genes)  IEA  
GO:0006355 [list] [network] regulation of transcription, DNA-templated  (2066 genes)  IEA  
GO CC
GO:0000790 [list] [network] nuclear chromatin  (218 genes)  ISO  
GO:0005667 [list] [network] transcription factor complex  (258 genes)  IPI  
GO:0016604 [list] [network] nuclear body  (283 genes)  ISO  
GO:0005654 [list] [network] nucleoplasm  (1912 genes)  ISO  
GO:0005634 [list] [network] nucleus  (5524 genes)  IDA ISO  
GO:0005737 [list] [network] cytoplasm  (6086 genes)  IDA  
GO MF
GO:0001225 [list] [network] RNA polymerase II transcription coactivator binding  (2 genes)  ISO  
GO:0048273 [list] [network] mitogen-activated protein kinase p38 binding  (7 genes)  IPI  
GO:0001205 [list] [network] transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding  (34 genes)  IDA  
GO:0001085 [list] [network] RNA polymerase II transcription factor binding  (60 genes)  IPI  
GO:0000980 [list] [network] RNA polymerase II distal enhancer sequence-specific DNA binding  (63 genes)  IDA  
GO:0003705 [list] [network] transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  (67 genes)  IDA  
GO:0001227 [list] [network] transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding  (72 genes)  IDA  
GO:0000977 [list] [network] RNA polymerase II regulatory region sequence-specific DNA binding  (252 genes)  ISO  
GO:0001077 [list] [network] transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding  (285 genes)  IDA  
GO:0000978 [list] [network] RNA polymerase II proximal promoter sequence-specific DNA binding  (423 genes)  IDA  
GO:0003682 [list] [network] chromatin binding  (444 genes)  IDA  
GO:0043565 [list] [network] sequence-specific DNA binding  (559 genes)  IDA  
GO:0003700 [list] [network] DNA-binding transcription factor activity  (816 genes)  IEA  
GO:0003677 [list] [network] DNA binding  (1709 genes)  IDA  
GO:0005515 [list] [network] protein binding  (4163 genes)  IPI  
KEGG mmu04010 MAPK signaling pathway
mmu04022 cGMP-PKG signaling pathway
mmu04024 cAMP signaling pathway
mmu04218 Cellular senescence
mmu04310 Wnt signaling pathway
mmu04380 Osteoclast differentiation
mmu04650 Natural killer cell mediated cytotoxicity
mmu04658 Th1 and Th2 cell differentiation
mmu04659 Th17 cell differentiation
mmu04660 T cell receptor signaling pathway
mmu04662 B cell receptor signaling pathway
mmu04921 Oxytocin signaling pathway
mmu04933 AGE-RAGE signaling pathway in diabetic complications
mmu05161 Hepatitis B
mmu05166 HTLV-I infection
mmu05167 Kaposi's sarcoma-associated herpesvirus infection
mmu05321 Inflammatory bowel disease (IBD)
Orthologous [Ortholog page] NFATC1 (hsa)NFATC1 (gga)NFATC1 (cfa)nfatc1 (dre)NFATC1 (mcc)Nfatc1 (rno)
Subcellular
localization
nucl 8,  cyto_nucl 5,  cyto 2  (predict for NP_001157581.1)
nucl 8,  cyto_nucl 5,  cyto 1  (predict for NP_001157582.1)
nucl 9,  cyto_nucl 5  (predict for NP_001157583.1)
nucl 8,  cyto_nucl 5  (predict for NP_001157584.1)
nucl 9,  cyto_nucl 5  (predict for NP_058071.2)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for NP_940821.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04010 MAPK signaling pathway 5
mmu04218 Cellular senescence 3
mmu04659 Th17 cell differentiation 3
mmu04015 Rap1 signaling pathway 2
mmu04380 Osteoclast differentiation 2
Genes directly connected with Nfatc1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
1400.4 Sh2b3 SH2B adaptor protein 3 [detail] 16923
1653.8 Rin3 Ras and Rab interactor 3 [detail] 217835
1722.2 Tgfbr2 transforming growth factor, beta receptor II [detail] 21813
1945.6 Runx1 runt related transcription factor 1 [detail] 12394
Coexpressed
gene list
[Coexpressed gene list for Nfatc1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 18018    
Refseq ID (protein) NP_001157581.1 
NP_001157582.1 
NP_001157583.1 
NP_001157584.1 
NP_058071.2 
NP_940821.1 


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