GO:0035591 signaling adaptor activity

79 hsa genes in this database.
68 mmu genes in this database.
68 rno genes in this database.
2 gga genes in this database.
41 dre genes in this database.
25 dme genes in this database.
13 cel genes in this database.
8 sce genes in this database.
13 spo genes in this database.

[QuickGO]

term: signaling adaptor activity
goid: GO:0035591

Shaded genes do not have GeneChip data. The output was limited up to 100 for each of species.
Species Symbol Gene
coexpression		 Locus
page 		Full name* Entrez Gene ID Evidence*
hsa CD3E CD3e molecule 916
hsa CD3G CD3g molecule 917
hsa CRK CRK proto-oncogene, adaptor protein 1398 IBA,IDA
hsa CRKL CRK like proto-oncogene, adaptor protein 1399 IBA
hsa EPS8 epidermal growth factor receptor pathway substrate 8 2059 IEA
hsa GNB1 G protein subunit beta 1 2782
hsa GNB2 G protein subunit beta 2 2783
hsa GNB3 G protein subunit beta 3 2784
hsa GRB10 growth factor receptor bound protein 10 2887
hsa IRS1 insulin receptor substrate 1 3667
hsa NCK1 NCK adaptor protein 1 4690 IBA,NAS
hsa PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 5295
hsa MAP2K1 mitogen-activated protein kinase kinase 1 5604
hsa MAP2K2 mitogen-activated protein kinase kinase 2 5605
hsa PTPN11 protein tyrosine phosphatase non-receptor type 11 5781
hsa SHC1 SHC adaptor protein 1 6464
hsa AXIN1 axin 1 8312 TAS
hsa NCK2 NCK adaptor protein 2 8440 IBA,NAS
hsa TRADD TNFRSF1A associated via death domain 8717
hsa IQGAP1 IQ motif containing GTPase activating protein 1 8826
hsa SOCS2 suppressor of cytokine signaling 2 8835
hsa KSR1 kinase suppressor of ras 1 8844
hsa SPAG9 sperm associated antigen 9 9043
hsa DOK2 docking protein 2 9046
hsa DLG5 discs large MAGUK scaffold protein 5 9231
hsa HOMER2 homer scaffold protein 2 9455
hsa HOMER1 homer scaffold protein 1 9456 IC
hsa MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 9479
hsa SPATA2 spermatogenesis associated 2 9825
hsa GAB2 GRB2 associated binding protein 2 9846
hsa MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 9863
hsa G3BP2 G3BP stress granule assembly factor 2 9908
hsa ABI1 abl interactor 1 10006 IDA,ISS
hsa SH2B3 SH2B adaptor protein 3 10019
hsa ABI2 abl interactor 2 10152 IDA
hsa RACK1 receptor for activated C kinase 1 10399 IMP
hsa SORBS1 sorbin and SH3 domain containing 1 10580
hsa SH2B2 SH2B adaptor protein 2 10603 IDA
hsa RGS14 regulator of G protein signaling 14 10636
hsa KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 10657 IDA
hsa GNB5 G protein subunit beta 5 10681
hsa FRS3 fibroblast growth factor receptor substrate 3 10817
hsa FRS2 fibroblast growth factor receptor substrate 2 10818
hsa AKAP13 A-kinase anchoring protein 13 11214
hsa SHANK2 SH3 and multiple ankyrin repeat domains 2 22941
hsa SARM1 sterile alpha and TIR motif containing 1 23098 IEA
hsa MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 23162
hsa GRIP1 glutamate receptor interacting protein 1 23426
hsa MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 23542
hsa NUP62 nucleoporin 62 23636
hsa SH2B1 SH2B adaptor protein 1 25970
hsa LDLRAP1 low density lipoprotein receptor adaptor protein 1 26119 IDA
hsa STAP1 signal transducing adaptor family member 1 26228 IBA,IPI
hsa LAT linker for activation of T cells 27040
hsa BLNK B cell linker 29760 IDA
hsa CARD10 caspase recruitment domain family member 10 29775
hsa TRAT1 T cell receptor associated transmembrane adaptor 1 50852
hsa SHANK1 SH3 and multiple ankyrin repeat domains 1 50944
hsa STAP2 signal transducing adaptor family member 2 55620 IEA
hsa PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 55824 NAS
hsa CDC42SE2 CDC42 small effector 2 56990 IDA
hsa MAVS mitochondrial antiviral signaling protein 57506 IMP
hsa SH3RF1 SH3 domain containing ring finger 1 57630
hsa GNB4 G protein subunit beta 4 59345
hsa SAV1 salvador family WW domain containing protein 1 60485
hsa MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component 64210
hsa FCRL2 Fc receptor like 2 79368 IDA
hsa ZDHHC11 zinc finger DHHC-type containing 11 79844 IDA
hsa GRIP2 glutamate receptor interacting protein 2 80852
hsa SLA2 Src like adaptor 2 84174 IDA
hsa AFAP1L2 actin filament associated protein 1 like 2 84632 IEA
hsa SHANK3 SH3 and multiple ankyrin repeat domains 3 85358
hsa LRRK2 leucine rich repeat kinase 2 120892
hsa DUSP19 dual specificity phosphatase 19 142679
hsa MPP7 membrane palmitoylated protein 7 143098 NAS,TAS
hsa ROPN1B rhophilin associated tail protein 1B 152015
hsa DAB2IP DAB2 interacting protein 153090 IDA
hsa DEDD2 death effector domain containing 2 162989
hsa GRAPL GRB2 related adaptor protein like 400581 IBA
mmu Abi1 abl interactor 1 11308 IDA,ISO
mmu Axin1 axin 1 12005
mmu Crk v-crk avian sarcoma virus CT10 oncogene homolog 12928 IBA,ISO
mmu Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like 12929 IBA
mmu Dok2 docking protein 2 13449
mmu Eps8 epidermal growth factor receptor pathway substrate 8 13860 IEA
mmu Gab2 growth factor receptor bound protein 2-associated protein 2 14389
mmu Gnb1 guanine nucleotide binding protein (G protein), beta 1 14688
mmu Gnb2 guanine nucleotide binding protein (G protein), beta 2 14693
mmu Rack1 receptor for activated C kinase 1 14694 ISO
mmu Gnb3 guanine nucleotide binding protein (G protein), beta 3 14695
mmu Gnb4 guanine nucleotide binding protein (G protein), beta 4 14696
mmu Gnb5 guanine nucleotide binding protein (G protein), beta 5 14697
mmu Grb10 growth factor receptor bound protein 10 14783
mmu Irs1 insulin receptor substrate 1 16367
mmu Ksr1 kinase suppressor of ras 1 16706
mmu Lat linker for activation of T cells 16797
mmu Sh2b3 SH2B adaptor protein 3 16923 IEA
mmu Blnk B cell linker 17060 ISO
mmu Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 17973 IBA
mmu Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 17974 IBA
mmu Nup62 nucleoporin 62 18226
mmu Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 19099
mmu Ptpn11 protein tyrosine phosphatase, non-receptor type 11 19247
mmu Pxn paxillin 19303
mmu Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 20218 IDA,ISO
mmu Sh2b1 SH2B adaptor protein 1 20399 IEA
mmu Sorbs1 sorbin and SH3 domain containing 1 20411
mmu Sh2b2 SH2B adaptor protein 2 23921 IDA,ISO
mmu Map2k1 mitogen-activated protein kinase kinase 1 26395
mmu Map2k2 mitogen-activated protein kinase kinase 2 26396
mmu Homer2 homer scaffolding protein 2 26557
mmu Sh2d1b1 SH2 domain containing 1B1 26904 NAS
mmu Sh2d3c SH2 domain containing 3C 27387
mmu Iqgap1 IQ motif containing GTPase activating protein 1 29875
mmu Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 30957
mmu Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 50791
mmu Rgs14 regulator of G-protein signaling 14 51791
mmu Stap1 signal transducing adaptor family member 1 56792 IBA,ISO
mmu Shank3 SH3 and multiple ankyrin repeat domains 3 58234
mmu Sh3rf1 SH3 domain containing ring finger 1 59009
mmu Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 60597
mmu Sav1 salvador family WW domain containing 1 64010
mmu Lrrk2 leucine-rich repeat kinase 2 66725
mmu Dusp19 dual specificity phosphatase 19 68082
mmu Dab2ip disabled 2 interacting protein 69601 ISO
mmu Spag9 sperm associated antigen 9 70834
mmu Zdhhc11 zinc finger, DHHC domain containing 11 71164 ISO
mmu Tradd TNFRSF1A-associated via death domain 71609
mmu Cdc42se2 CDC42 small effector 2 72729 ISO
mmu Grip1 glutamate receptor interacting protein 1 74053
mmu Akap13 A kinase (PRKA) anchor protein 13 75547
mmu Sla2 Src-like-adaptor 2 77799 ISO
mmu Fcrls Fc receptor-like S, scavenger receptor 80891 ISO
mmu Akap12 A kinase (PRKA) anchor protein (gravin) 12 83397
mmu Ldlrap1 low density lipoprotein receptor adaptor protein 1 100017 ISO
mmu Stap2 signal transducing adaptor family member 2 106766 IEA
mmu Frs3 fibroblast growth factor receptor substrate 3 107971
mmu Shank2 SH3 and multiple ankyrin repeat domains 2 210274
mmu Socs2 suppressor of cytokine signaling 2 216233
mmu Afap1l2 actin filament associated protein 1-like 2 226250 IEA
mmu Mavs mitochondrial antiviral signaling protein 228607 IMP,ISO
mmu Sarm1 sterile alpha and HEAT/Armadillo motif containing 1 237868 IEA
mmu Shank1 SH3 and multiple ankyrin repeat domains 1 243961
mmu Spata2 spermatogenesis associated 2 263876
mmu Frs2 fibroblast growth factor receptor substrate 2 327826
mmu Abi2 abl interactor 2 329165 ISO
mmu Ksr2 kinase suppressor of ras 2 333050
rno Gnb1 G protein subunit beta 1 24400
rno Irs1 insulin receptor substrate 1 25467
rno Ptpn11 protein tyrosine phosphatase, non-receptor type 11 25622
rno Homer2 homer scaffold protein 2 29547
rno Crk CRK proto-oncogene, adaptor protein 54245 IBA,ISO
rno Sh2b3 SH2B adaptor protein 3 58838
rno Map2k2 mitogen activated protein kinase kinase 2 58960
rno Shank3 SH3 and multiple ankyrin repeat domains 3 59312
rno Gnb3 G protein subunit beta 3 60449
rno Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 64019
rno Pdlim5 PDZ and LIM domain 5 64353
rno Nup62 nucleoporin 62 65274
rno Shank1 SH3 and multiple ankyrin repeat domains 1 78957
rno Abi1 abl-interactor 1 79249 IEA,ISO
rno Axin1 axin 1 79257
rno Lat linker for activation of T cells 81511
rno Gnb2 G protein subunit beta 2 81667
rno Rack1 receptor for activated C kinase 1 83427 ISO
rno Gnb5 G protein subunit beta 5 83579
rno Grip1 glutamate receptor interacting protein 1 84016
rno Gab2 GRB2-associated binding protein 2 84477
rno Socs2 suppressor of cytokine signaling 2 84607
rno Sh2b1 SH2B adaptor protein 1 89817 IEA
rno Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 113970
rno Sh2b2 SH2B adaptor protein 2 114203 ISO
rno Spata2 spermatogenesis associated 2 114210
rno Rgs14 regulator of G-protein signaling 14 114705
rno Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 116457
rno Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 117268 ISO
rno Map2k1 mitogen activated protein kinase kinase 1 170851
rno Shank2 SH3 and multiple ankyrin repeat domains 2 171093
rno Grip2 glutamate receptor interacting protein 2 171571
rno Dab2ip DAB2 interacting protein 192126 IEA,ISO
rno Tradd TNFRSF1A-associated via death domain 246756
rno Abi2 abl-interactor 2 286928 ISO
rno Sarm1 sterile alpha and TIR motif containing 1 287545 IEA
rno Crkl CRK like proto-oncogene, adaptor protein 287942 IBA
rno Ksr2 kinase suppressor of ras 2 288691
rno Dok2 docking protein 2 290361
rno Afap1l2 actin filament associated protein 1-like 2 292130 IEA
rno Akap13 A-kinase anchoring protein 13 293024
rno Gnb4 G protein subunit beta 4 294962
rno Sav1 salvador family WW domain containing protein 1 299116
rno Nck1 NCK adaptor protein 1 300955 IBA
rno Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 302983
rno Stap1 signal transducing adaptor family member 1 305269 IBA,ISO
rno Sh3rf1 SH3 domain containing ring finger 1 306417
rno Fcrl2 Fc receptor-like 2 310694 ISO
rno Dusp19 dual specificity phosphatase 19 311151
rno Mavs mitochondrial antiviral signaling protein 311430 ISO
rno Eps8 epidermal growth factor receptor pathway substrate 8 312812 IEA
rno Frs2 fibroblast growth factor receptor substrate 2 314850
rno Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 315220
rno Frs3 fibroblast growth factor receptor substrate 3 316213
rno Nck2 NCK adaptor protein 2 316369 IBA
rno Spag9 sperm associated antigen 9 360600
rno Pxn paxillin 360820
rno Iqgap1 IQ motif containing GTPase activating protein 1 361598
rno Stap2 signal transducing adaptor family member 2 363334 IEA
rno Grb10 growth factor receptor bound protein 10 498416
rno Zdhhc11 zinc finger, DHHC-type containing 11 499000 ISO
rno Blnk B-cell linker 499356 ISO
rno Sla2 Src-like-adaptor 2 499931 ISO
rno Ldlrap1 low density lipoprotein receptor adaptor protein 1 500564 ISO
rno Sorbs1 sorbin and SH3 domain containing 1 686098
rno Cdc42se2 CDC42 small effector 2 691031 IEA,ISO
rno LOC100362023 CDC42 small effector 2-like 100362023 IEA
rno Ksr1 kinase suppressor of ras 1 108348076
gga PTPN11 protein tyrosine phosphatase non-receptor type 11 395815
gga RACK1 receptor for activated C kinase 1 417044 IEA
dre tradd tnfrsf1a-associated via death domain 58130
dre gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 322104
dre stap2a signal transducing adaptor family member 2a 327172 IEA
dre akap13 A-kinase anchoring protein 13 327519
dre eps8a epidermal growth factor receptor pathway substrate 8a 393212 IEA
dre gnb5b guanine nucleotide binding protein (G protein), beta 5b 393719
dre si:dkey-172h23.2 si:dkey-172h23.2 393772
dre nck2a NCK adaptor protein 2a 393972 IBA,IEA
dre sarm1 sterile alpha and TIR motif containing 1 403143 IEA
dre gnb3b guanine nucleotide binding protein (G protein), beta polypeptide 3b 406483
dre stap2b signal transducing adaptor family member 2b 406601 IEA
dre gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b 406796
dre gnb3a guanine nucleotide binding protein (G protein), beta polypeptide 3a 436710
dre frs2b fibroblast growth factor receptor substrate 2b 436931
dre nck2b NCK adaptor protein 2b 445098 IBA
dre crk v-crk avian sarcoma virus CT10 oncogene homolog 445234 IBA
dre gnb4b guanine nucleotide binding protein (G protein), beta polypeptide 4b 492811
dre gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 541370
dre crkl v-crk avian sarcoma virus CT10 oncogene homolog-like 556443 IBA
dre sh3rf1 SH3 domain containing ring finger 1 556523
dre shank3a SH3 and multiple ankyrin repeat domains 3a 557701
dre grip1 glutamate receptor interacting protein 1 558006
dre sh2b1 SH2B adaptor protein 1 558152 IEA
dre spag9a sperm associated antigen 9a 558833
dre frs2a fibroblast growth factor receptor substrate 2a 559479
dre socs2 suppressor of cytokine signaling 2 562062
dre grip2b glutamate receptor interacting protein 2b 562290
dre gnb5a guanine nucleotide binding protein (G protein), beta 5a 562813
dre magi2a membrane associated guanylate kinase, WW and PDZ domain containing 2a 564112
dre nck1a NCK adaptor protein 1a 564584 IBA
dre shank3b SH3 and multiple ankyrin repeat domains 3b 566152
dre afap1l2 actin filament associated protein 1-like 2 567369 IEA
dre shank2b SH3 and multiple ankyrin repeat domains 2b 567595
dre grip2a glutamate receptor interacting protein 2a 568084
dre sla2b Src like adaptor 2b 568515 IBA
dre shank2a SH3 and multiple ankyrin repeat domains 2a 572407
dre si:dkey-17m8.1 si:dkey-17m8.1 796618
dre mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 100318355
dre frs3 fibroblast growth factor receptor substrate 3 100330147
dre nck1b NCK adaptor protein 1b 100334953 IBA
dre sh2b3 SH2B adaptor protein 3 101884640 IEA
dme Gbeta5 Gbeta5 31744
dme dsh dishevelled 32078
dme hep hemipterous 32256
dme Gbeta13F G protein beta-subunit 13F 32544
dme dock dreadlocks 33262 IBA
dme CG13398 uncharacterized protein 34169
dme CG44085 uncharacterized protein 34732
dme cos costa 35653 IDA
dme Myd88 Myd88 35956 IMP
dme drk downstream of receptor kinase 36497
dme ckn caskin 36673 IBA,IPI
dme cnk connector enhancer of ksr 36952
dme inaD inactivation no afterpotential D 37629
dme Sarm Sterile alpha and Armadillo motif 38895 IEA
dme Gbeta76C G protein beta-subunit 76C 40148
dme ksr kinase suppressor of ras 40660
dme stumps stumps 41770
dme Lnk Lnk 43130
dme CG15529 uncharacterized protein 43584 ISS
dme Crk Crk oncogene 43775 IBA
dme syd sunday driver 43905
dme csw corkscrew 45278
dme wek weckle 48785 IDA
dme Prosap prosap 50225
dme Aplip1 APP-like protein interacting protein 1 53472
cel gpb-2 Guanine nucleotide-binding protein subunit beta-2 172483
cel mig-5 Segment polarity protein dishevelled homolog mig-5 174317 IC
cel shn-1 Protein shank 174739
cel gpb-1 Guanine nucleotide-binding protein subunit beta-1;WD_REPEATS_REGION domain-containing protein 174803
cel tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein tir-1 175502 IDA,IEA
cel unc-16 JNK-interacting protein 176349
cel ced-2 Cell death abnormality protein 2;SH3 domain-containing protein 176968 IBA
cel num-1 Numb-related protein 1;PID domain-containing protein 180367
cel nck-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family 180690 IBA
cel ist-1 Insulin receptor SubsTrate homolog 180978
cel syd-2 Liprin-alpha 181255
cel gap-3 GTPase Activating Protein family 260016 IBA
cel dsh-2 DiSHevelled related 266854 IC
sce SPA2 Spa2p 850639
sce SPH1 Sph1p 851023
sce AHK1 Ahk1p 851486
sce STE5 Ste5p 851680
sce PBS2 mitogen-activated protein kinase kinase PBS2 853313
sce STE4 G protein subunit beta 854387
sce NUD1 Nud1p 854555 IMP,IPI
sce SHO1 osmosensor SHO1 856854
spo cdc11 SIN component scaffold protein cdc11 2539149 EXP
spo git5 heterotrimeric G protein beta subunit Git5 2539974
spo sid4 SIN component scaffold protein Sid4 2540650 EXP
spo cut12 protein Cut12 2541141 IPI
spo SPBC887.09c putative leucine-rich repeat protein Sog2 2541171 EXP
spo byr4 two-component GAP Byr4 2541936 EXP
spo SPAC7D4.03c hypothetical protein 2542089
spo spg1 GTPase Spg1 2542761 IDA
spo sin1 MAP kinase-interacting protein Sin1 2542972 IDA
spo mrc1 protein mrc1 2543240 IGI
spo rad4 BRCT domain protein Rad4 2543281 IDA,IGI
spo SPAC3G9.05 putative GTPase-activating protein 2543517
spo rad9 checkpoint clamp complex protein Rad9 2543544 IGI


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