GO:0035591 signaling adaptor activity

79 hsa genes in COXPRESdb.
52 mmu genes in COXPRESdb.
48 rno genes in COXPRESdb.
4 gga genes in COXPRESdb.
33 dre genes in COXPRESdb.
11 dme genes in COXPRESdb.
8 cel genes in COXPRESdb.
4 sce genes in COXPRESdb.
1 spo genes in COXPRESdb.

[QuickGO]

term: signaling adaptor activity
goid: GO:0035591


Shaded genes do not have GeneChip data. The output was limited up to 300 for each of species.
Species Symbol Supportability of
expression data
Gene
coexpression
Locus
page
Full name* Entrez Gene ID Evidence*
hsa ARHGAP1 ☆☆☆ Rho GTPase activating protein 1 392
hsa ARHGAP4 ☆☆☆ Rho GTPase activating protein 4 393
hsa ARHGAP6 ☆☆ Rho GTPase activating protein 6 395
hsa CD28 ☆☆☆ CD28 molecule 940
hsa CHN1 ☆☆ chimerin 1 1123
hsa CHN2 ☆☆ chimerin 2 1124
hsa CRK ☆☆ CRK proto-oncogene, adaptor protein 1398
hsa CRKL ☆☆☆ CRK like proto-oncogene, adaptor protein 1399
hsa EPS8 ☆☆☆ epidermal growth factor receptor pathway substrate 8 2059
hsa GAB1 ☆☆ GRB2 associated binding protein 1 2549
hsa GRB2 ☆☆☆ growth factor receptor bound protein 2 2885
hsa GRB7 ☆☆☆ growth factor receptor bound protein 7 2886
hsa GRB10 ☆☆☆ growth factor receptor bound protein 10 2887
hsa GRB14 ☆☆ growth factor receptor bound protein 14 2888
hsa IRS1 insulin receptor substrate 1 3667
hsa LASP1 ☆☆☆ LIM and SH3 protein 1 3927
hsa SH2D1A ☆☆☆ SH2 domain containing 1A 4068
hsa NCK1 ☆☆ NCK adaptor protein 1 4690
hsa PIK3R1 ☆☆ phosphoinositide-3-kinase regulatory subunit 1 5295
hsa PTPN11 protein tyrosine phosphatase, non-receptor type 11 5781
hsa SH3BGR ☆☆ SH3 domain binding glutamate rich protein 6450
hsa SH3BGRL ☆☆☆ SH3 domain binding glutamate rich protein like 6451
hsa SH3BP2 ☆☆☆ SH3 domain binding protein 2 6452
hsa SHB ☆☆ SH2 domain containing adaptor protein B 6461
hsa SHC1 ☆☆ SHC adaptor protein 1 6464
hsa SLA ☆☆☆ Src like adaptor 6503
hsa SRC ☆☆ SRC proto-oncogene, non-receptor tyrosine kinase 6714
hsa TP53BP2 ☆☆☆ tumor protein p53 binding protein 2 7159
hsa STAM ☆☆ signal transducing adaptor molecule 8027
hsa BCAR3 ☆☆ BCAR3, NSP family adaptor protein 8412
hsa NCK2 NCK adaptor protein 2 8440
hsa IRS4 insulin receptor substrate 4 8471
hsa CNTNAP1 ☆☆☆ contactin associated protein 1 8506
hsa SKAP1 ☆☆☆ src kinase associated phosphoprotein 1 8631
hsa SOCS2 ☆☆ suppressor of cytokine signaling 2 8835
hsa KSR1 ☆☆ kinase suppressor of ras 1 8844
hsa SKAP2 ☆☆☆ src kinase associated phosphoprotein 2 8935
hsa SPAG9 ☆☆☆ sperm associated antigen 9 9043
hsa DOK2 ☆☆☆ docking protein 2 9046
hsa SH2D2A ☆☆☆ SH2 domain containing 2A 9047
hsa GRAP2 ☆☆☆ GRB2-related adaptor protein 2 9402
hsa HOMER1 homer scaffolding protein 1 9456 IC
hsa MAPK8IP1 ☆☆ mitogen-activated protein kinase 8 interacting protein 1 9479
hsa GAB2 ☆☆ GRB2 associated binding protein 2 9846
hsa SH2B3 SH2B adaptor protein 3 10019 IEA
hsa SH2D3C ☆☆☆ SH2 domain containing 3C 10044
hsa SH2D3A ☆☆☆ SH2 domain containing 3A 10045
hsa TOB1 ☆☆☆ transducer of ERBB2, 1 10140
hsa RACK1 ☆☆☆ receptor for activated C kinase 1 10399 IMP
hsa VAV3 vav guanine nucleotide exchange factor 3 10451
hsa SORBS1 ☆☆ sorbin and SH3 domain containing 1 10580
hsa SH2B2 ☆☆ SH2B adaptor protein 2 10603
hsa KHDRBS1 ☆☆☆ KH RNA binding domain containing, signal transduction associated 1 10657
hsa GRAP ☆☆☆ GRB2-related adaptor protein 10750
hsa FRS2 ☆☆ fibroblast growth factor receptor substrate 2 10818
hsa AKAP13 ☆☆☆ A-kinase anchoring protein 13 11214
hsa MAPK8IP3 ☆☆☆ mitogen-activated protein kinase 8 interacting protein 3 23162
hsa MAPK8IP2 ☆☆☆ mitogen-activated protein kinase 8 interacting protein 2 23542
hsa RUSC1 ☆☆ RUN and SH3 domain containing 1 23623
hsa SH2B1 ☆☆☆ SH2B adaptor protein 1 25970 IEA
hsa LDLRAP1 low density lipoprotein receptor adaptor protein 1 26119 IDA
hsa STAP1 ☆☆☆ signal transducing adaptor family member 1 26228
hsa LAT linker for activation of T cells 27040
hsa BLNK ☆☆☆ B cell linker 29760
hsa ITSN2 ☆☆☆ intersectin 2 50618
hsa TRAT1 ☆☆☆ T cell receptor associated transmembrane adaptor 1 50852
hsa PAG1 ☆☆ phosphoprotein membrane anchor with glycosphingolipid microdomains 1 55824
hsa SHD Src homology 2 domain containing transforming protein D 56961
hsa FCRL2 ☆☆☆ Fc receptor like 2 79368
hsa SLA2 ☆☆☆ Src like adaptor 2 84174
hsa AFAP1L2 ☆☆ actin filament associated protein 1 like 2 84632 IEA
hsa HSH2D ☆☆☆ hematopoietic SH2 domain containing 84941
hsa SHF ☆☆ Src homology 2 domain containing F 90525
hsa CLNK ☆☆☆ cytokine dependent hematopoietic cell linker 116449
hsa SHE ☆☆☆ Src homology 2 domain containing E 126669
hsa DUSP19 ☆☆☆ dual specificity phosphatase 19 142679
hsa MPP7 ☆☆ membrane palmitoylated protein 7 143098 NAS,TAS
hsa DAB2IP ☆☆ DAB2 interacting protein 153090 IDA
hsa SH2D6 SH2 domain containing 6 284948
mmu Cd28 ☆☆☆ CD28 antigen 12487
mmu Crk v-crk avian sarcoma virus CT10 oncogene homolog 12928
mmu Dok2 ☆☆☆ docking protein 2 13449
mmu Eps8 ☆☆ epidermal growth factor receptor pathway substrate 8 13860 IEA
mmu Gab2 ☆☆ growth factor receptor bound protein 2-associated protein 2 14389
mmu Rack1 ☆☆☆ receptor for activated C kinase 1 14694 ISO
mmu Grb10 ☆☆☆ growth factor receptor bound protein 10 14783
mmu Grb2 ☆☆ growth factor receptor bound protein 2 14784
mmu Grb7 ☆☆☆ growth factor receptor bound protein 7 14786
mmu Irs1 ☆☆ insulin receptor substrate 1 16367
mmu Ksr1 kinase suppressor of ras 1 16706
mmu Lat ☆☆☆ linker for activation of T cells 16797
mmu Sh2b3 ☆☆☆ SH2B adaptor protein 3 16923 IEA
mmu Blnk ☆☆☆ B cell linker 17060
mmu Nck1 ☆☆ non-catalytic region of tyrosine kinase adaptor protein 1 17973
mmu Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 17974
mmu Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 19099
mmu Ptpn11 ☆☆ protein tyrosine phosphatase, non-receptor type 11 19247
mmu Khdrbs1 ☆☆☆ KH domain containing, RNA binding, signal transduction associated 1 20218
mmu Sh2b1 ☆☆ SH2B adaptor protein 1 20399 IEA
mmu Sh2d1a ☆☆☆ SH2 domain containing 1A 20400
mmu Sorbs1 ☆☆ sorbin and SH3 domain containing 1 20411
mmu Shd src homology 2 domain-containing transforming protein D 20420
mmu Sla ☆☆☆ src-like adaptor 20491
mmu Sh2b2 SH2B adaptor protein 2 23921 IEA
mmu Sh3bp2 ☆☆☆ SH3-domain binding protein 2 24055
mmu Sh2d2a ☆☆☆ SH2 domain containing 2A 27371
mmu Sh2d3c ☆☆☆ SH2 domain containing 3C 27387
mmu Bcar3 ☆☆ breast cancer anti-estrogen resistance 3 29815
mmu Mapk8ip3 ☆☆☆ mitogen-activated protein kinase 8 interacting protein 3 30957
mmu Grb14 ☆☆ growth factor receptor bound protein 14 50915
mmu Skap2 ☆☆ src family associated phosphoprotein 2 54353
mmu Stap1 ☆☆☆ signal transducing adaptor family member 1 56792
mmu Dusp19 ☆☆☆ dual specificity phosphatase 19 68082
mmu Dab2ip ☆☆ disabled 2 interacting protein 69601 ISO
mmu Spag9 ☆☆ sperm associated antigen 9 70834
mmu Sh2d6 SH2 domain containing 6 71130
mmu Akap13 ☆☆ A kinase (PRKA) anchor protein 13 75547
mmu Sla2 ☆☆☆ Src-like-adaptor 2 77799
mmu Skap1 ☆☆☆ src family associated phosphoprotein 1 78473
mmu Pag1 ☆☆ phosphoprotein associated with glycosphingolipid microdomains 1 94212
mmu Ldlrap1 ☆☆ low density lipoprotein receptor adaptor protein 1 100017 ISO
mmu Rapgef1 ☆☆ Rap guanine nucleotide exchange factor (GEF) 1 107746
mmu Khdrbs2 ☆☆ KH domain containing, RNA binding, signal transduction associated 2 170771
mmu Hsh2d ☆☆☆ hematopoietic SH2 domain containing 209488
mmu She ☆☆☆ src homology 2 domain-containing transforming protein E 214547
mmu Socs2 ☆☆ suppressor of cytokine signaling 2 216233
mmu Afap1l2 ☆☆ actin filament associated protein 1-like 2 226250 IEA
mmu Shb ☆☆ src homology 2 domain-containing transforming protein B 230126
mmu Frs2 fibroblast growth factor receptor substrate 2 327826
mmu Ksr2 kinase suppressor of ras 2 333050
mmu Shf Src homology 2 domain containing F 435684
rno Irs1 insulin receptor substrate 1 25467
rno Ptpn11 ☆☆ protein tyrosine phosphatase, non-receptor type 11 25622
rno Cd28 ☆☆ Cd28 molecule 25660
rno Crk CRK proto-oncogene, adaptor protein 54245
rno Sh2b3 SH2B adaptor protein 3 58838 IEA
rno Grb14 growth factor receptor bound protein 14 58844
rno Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 64019
rno Grb2 ☆☆ growth factor receptor bound protein 2 81504
rno Lat ☆☆☆ linker for activation of T cells 81511
rno Rack1 ☆☆☆ receptor for activated C kinase 1 83427 ISO
rno Grb7 ☆☆ growth factor receptor bound protein 7 84427
rno Gab2 GRB2-associated binding protein 2 84477
rno Socs2 suppressor of cytokine signaling 2 84607
rno Sh2b1 ☆☆ SH2B adaptor protein 1 89817 IEA
rno Sh2b2 SH2B adaptor protein 2 114203
rno Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 116457
rno Khdrbs1 ☆☆ KH RNA binding domain containing, signal transduction associated 1 117268
rno Skap2 ☆☆ src kinase associated phosphoprotein 2 155183
rno Dab2ip DAB2 interacting protein 192126 IEA,ISO
rno Skap1 ☆☆☆ src kinase associated phosphoprotein 1 286975
rno Ksr2 kinase suppressor of ras 2 288691
rno Dok2 ☆☆☆ docking protein 2 290361
rno Afap1l2 ☆☆ actin filament associated protein 1-like 2 292130 IEA
rno Akap13 A-kinase anchoring protein 13 293024
rno Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 302983
rno Stap1 ☆☆☆ signal transducing adaptor family member 1 305269
rno Sh3bp2 SH3-domain binding protein 2 305450
rno Sh2d2a ☆☆ SH2 domain containing 2A 310688
rno Fcrl2 Fc receptor-like 2 310694
rno Bcar3 BCAR3, NSP family adaptor protein 310838
rno Dusp19 dual specificity phosphatase 19 311151
rno Eps8 epidermal growth factor receptor pathway substrate 8 312812 IEA
rno Frs2 fibroblast growth factor receptor substrate 2 314850
rno Nck2 NCK adaptor protein 2 316369
rno Shd src homology 2 domain-containing transforming protein D 316507
rno Sla ☆☆☆ src-like adaptor 338477
rno Ksr1 kinase suppressor of ras 1 360573
rno Spag9 ☆☆ sperm associated antigen 9 360600
rno Sh2d3c ☆☆☆ SH2 domain containing 3C 362111
rno Shb SH2 domain containing adaptor protein B 362513
rno Grb10 growth factor receptor bound protein 10 498416
rno Blnk ☆☆ B-cell linker 499356
rno Sla2 Src-like-adaptor 2 499931
rno Ldlrap1 low density lipoprotein receptor adaptor protein 1 500564 IEA,ISO
rno Sh2d1a ☆☆☆ SH2 domain containing 1A 501502
rno She ☆☆☆ Src homology 2 domain containing E 685088
rno Sorbs1 sorbin and SH3 domain containing 1 686098
rno Hsh2d ☆☆☆ hematopoietic SH2 domain containing 100360518
gga KHDRBS1 ☆☆ KH RNA binding domain containing, signal transduction associated 1 374071
gga BLNK B-cell linker 395733
gga PTPN11 protein tyrosine phosphatase, non-receptor type 11 395815
gga CD28 ☆☆ CD28 molecule 396249
dre skap2 src kinase associated phosphoprotein 2 368564
dre eps8 epidermal growth factor receptor pathway substrate 8 393212 IEA
dre grap2b ☆☆☆ GRB2-related adaptor protein 2b 393651
dre nck2a NCK adaptor protein 2a 393972
dre sh2d3cb SH2 domain containing 3Cb 394051
dre blnk B cell linker 405764
dre nck2b NCK adaptor protein 2b 445098
dre grb10a growth factor receptor-bound protein 10a 446167
dre grap2a ☆☆ GRB2-related adaptor protein 2a 550452
dre sh2b1 SH2B adaptor protein 1 558152 IEA
dre spag9a sperm associated antigen 9a 558833
dre sh2d3ca SH2 domain containing 3Ca 558860
dre shda Src homology 2 domain containing transforming protein D, a 561247
dre she ☆☆ Src homology 2 domain containing E 561493
dre socs2 suppressor of cytokine signaling 2 562062
dre si:ch211-253b1.3 si:ch211-253b1.3 563649
dre skap1 src kinase associated phosphoprotein 1 563784
dre shdb Src homology 2 domain containing transforming protein D, b 564537
dre nck1a NCK adaptor protein 1a 564584
dre afap1l2 actin filament associated protein 1-like 2 567369 IEA
dre sla2 Src-like-adaptor 2 568515
dre bcar3 BCAR3, NSP family adaptor protein 570610
dre sla1 Src-like-adaptor 1 571922
dre zgc:158464 zgc:158464 791139
dre si:dkey-17m8.1 si:dkey-17m8.1 796618
dre si:dkeyp-117b11.1 si:dkeyp-117b11.1 798129
dre pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 100034498
dre mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 100318355
dre si:ch73-116f3.3 si:ch73-116f3.3 100329864
dre nck1b NCK adaptor protein 1b 100334953
dre si:ch211-25d12.7 si:ch211-25d12.7 100536664
dre sh2b3 SH2B adaptor protein 3 101884640 IEA
dre si:dkey-220o5.5 si:dkey-220o5.5 101885767 IEA
dme CG43921 CG43921 gene product from transcript CG43921-RA 32202
dme dock dreadlocks 33262
dme CG9098 CG9098 gene product from transcript CG9098-RC 33840
dme CG44085 ☆☆☆ CG44085 gene product from transcript CG44085-RF 34732
dme drk downstream of receptor kinase 36497
dme ckn caskin 36673 IPI
dme dos ☆☆ daughter of sevenless 38321
dme PVRAP ☆☆ PVR adaptor protein 38677
dme Lnk ☆☆ CG17367 gene product from transcript CG17367-RC 43130 IEA
dme Crk ☆☆☆ Crk oncogene 43775
dme syd sunday driver 43905
cel mig-5 ☆☆ Segment polarity protein dishevelled homolog mig-5 174317 IC
cel tir-1 ☆☆ Sterile alpha and TIR motif-containing protein tir-1|TIR (Toll and Interleukin 1 Receptor) domain protein 175502 IDA
cel unc-16 JNK-interacting protein|hypothetical protein 176349
cel ced-2 Cell death abnormality protein 2|hypothetical protein 176968
cel num-1 NUMb related|Numb-related protein 1 180367
cel ist-1 Insulin receptor SubsTrate homolog 180978
cel sem-5 Sex muscle abnormal protein 5 181055
cel dsh-2 ☆☆☆ DiSHevelled related 266854 IC
sce SPA2 ☆☆☆ Spa2p 850639
sce AHK1 Ahk1p 851486
sce STE5 ☆☆ Ste5p 851680
sce SHO1 ☆☆ osmosensor SHO1 856854
spo conserved fungal family 2542089


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