[][] mmu  Wwp2 Gene
functional annotation
Function   WW domain containing E3 ubiquitin protein ligase 2
GO BP
GO:0006858 [list] [network] extracellular transport  (42 genes)  ISO  
GO:0070534 [list] [network] protein K63-linked ubiquitination  (50 genes)  IBA IMP  
GO:1901016 [list] [network] regulation of potassium ion transmembrane transporter activity  (63 genes)  ISO  
GO:0051865 [list] [network] protein autoubiquitination  (72 genes)  ISO  
GO:0032410 [list] [network] negative regulation of transporter activity  (87 genes)  ISO  
GO:0051224 [list] [network] negative regulation of protein transport  (138 genes)  ISO  
GO:0043433 [list] [network] negative regulation of DNA-binding transcription factor activity  (165 genes)  IDA  
GO:0045732 [list] [network] positive regulation of protein catabolic process  (221 genes)  IBA  
GO:0000209 [list] [network] protein polyubiquitination  (225 genes)  IBA  
GO:0043161 [list] [network] proteasome-mediated ubiquitin-dependent protein catabolic process  (298 genes)  IBA IMP ISO  
GO:0042391 [list] [network] regulation of membrane potential  (462 genes)  ISO  
GO:0016567 [list] [network] protein ubiquitination  (491 genes)  IBA IDA ISO  
GO:0034765 [list] [network] regulation of ion transmembrane transport  (497 genes)  IBA ISO  
GO:0006511 [list] [network] ubiquitin-dependent protein catabolic process  (498 genes)  IEA  
GO:0000122 [list] [network] negative regulation of transcription by RNA polymerase II  (948 genes)  IBA IDA ISO  
GO:0010629 [list] [network] negative regulation of gene expression  (1078 genes)  ISO  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (1250 genes)  IGI  
GO:0045892 [list] [network] negative regulation of transcription, DNA-templated  (1298 genes)  IDA  
GO CC
GO:0005634 [list] [network] nucleus  (7226 genes)  IDA ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IBA IDA  
GO MF
GO:0061630 [list] [network] ubiquitin protein ligase activity  (308 genes)  IBA IDA  
GO:0061629 [list] [network] RNA polymerase II-specific DNA-binding transcription factor binding  (323 genes)  IGI IPI ISO  
GO:0004842 [list] [network] ubiquitin-protein transferase activity  (413 genes)  IDA ISO  
GO:0008134 [list] [network] transcription factor binding  (673 genes)  ISO  
GO:0016740 [list] [network] transferase activity  (2235 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04120 [list] [network] Ubiquitin mediated proteolysis (147 genes)
Protein NP_080106.1  XP_006531362.1  XP_006531364.1 
BLAST NP_080106.1  XP_006531362.1  XP_006531364.1 
Orthologous [Ortholog page] WWP1 (hsa)WWP2 (hsa)Itch (mmu)Su(dx) (dme)ITCH (hsa)Wwp1 (mmu)wwp-1 (cel)Wwp2 (rno)Wwp1 (rno)Itch (rno)WWP2 (gga)ITCH (gga)WWP1 (gga)ITCH (cfa)WWP2 (cfa)wwp2 (dre)WWP1 (mcc)WWP2 (mcc)ITCH (mcc)itchb (dre)itcha (dre)WWP1 (cfa)ITCH (fca)WWP1 (fca)WWP2 (fca)
Subcellular
localization
wolf
mito 4,  nucl 4,  cyto_nucl 3,  cyto 2  (predict for NP_080106.1)
mito 4,  nucl 4,  cyto_nucl 3,  cyto 2  (predict for XP_006531362.1)
cyto 5,  cyto_nucl 5,  cyto_pero 3,  nucl 3,  cyto_mito 3,  cyto_plas 3  (predict for XP_006531364.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03040 Spliceosome 3
Genes directly connected with Wwp2 on the network
coex z* Locus Function* Coexpression
detail
CoexPub Entrez Gene ID*
5.9 Xab2 XPA binding protein 2 [detail] 0 67439
5.2 Sugp1 SURP and G patch domain containing 1 [detail] 0 70616
5.1 Chmp1a charged multivesicular body protein 1A [detail] 0 234852
Coexpressed
gene list
[Coexpressed gene list for Wwp2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 66894    
Refseq ID (protein) NP_080106.1 
XP_006531362.1 
XP_006531364.1 


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