| functional annotation |
| Function |
MAD2 mitotic arrest deficient-like 1 |
|
| GO BP |
|
GO:0090267 [list] [network] positive regulation of mitotic cell cycle spindle assembly checkpoint
|
(7 genes)
|
IMP
ISO
|
 |
|
GO:0051660 [list] [network] establishment of centrosome localization
|
(9 genes)
|
ISO
|
|
|
GO:1904667 [list] [network] negative regulation of ubiquitin protein ligase activity
|
(11 genes)
|
ISO
|
|
|
GO:0007094 [list] [network] mitotic spindle assembly checkpoint signaling
|
(27 genes)
|
IBA
IMP
ISA
ISO
|
|
|
GO:0045841 [list] [network] negative regulation of mitotic metaphase/anaphase transition
|
(29 genes)
|
TAS
|
|
|
GO:0000132 [list] [network] establishment of mitotic spindle orientation
|
(32 genes)
|
ISO
|
|
|
GO:0000070 [list] [network] mitotic sister chromatid segregation
|
(108 genes)
|
IMP
|
|
|
GO:0007093 [list] [network] mitotic cell cycle checkpoint signaling
|
(121 genes)
|
ISO
|
|
|
GO:0042177 [list] [network] negative regulation of protein catabolic process
|
(122 genes)
|
ISO
|
|
|
GO:0045930 [list] [network] negative regulation of mitotic cell cycle
|
(216 genes)
|
ISO
|
|
|
GO:0051301 [list] [network] cell division
|
(494 genes)
|
IEA
|
|
|
GO:0043066 [list] [network] negative regulation of apoptotic process
|
(968 genes)
|
IMP
ISO
|
|
|
GO:0007049 [list] [network] cell cycle
|
(1198 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0008022 [list] [network] protein C-terminus binding
|
(232 genes)
|
ISO
|
|
|
GO:0042803 [list] [network] protein homodimerization activity
|
(780 genes)
|
ISO
|
|
|
GO:0042802 [list] [network] identical protein binding
|
(2357 genes)
|
ISO
|
|
|
GO:0005515 [list] [network] protein binding
|
(9507 genes)
|
IPI
|
|
|
| KEGG |
mmu04110 [list] [network] Cell cycle (125 genes) |
 |
| mmu04114 [list] [network] Oocyte meiosis (121 genes) |
|
| mmu04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes) |
|
| mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes) |
|
| Protein |
NP_001342553.1
NP_062372.2
|
| BLAST |
NP_001342553.1
NP_062372.2
|
| Orthologous |
[Ortholog page]
MAD2L1 (hsa)
mad2 (dme)
mdf-2 (cel)
Mad2l1 (rno)
MAD2L1 (gga)
LOC476070 (cfa)
mad2l1 (dre)
MAD2L1 (mcc)
MAD2 (sce)
MAD2L1 (fca)
MAD2L1 (cfa)
|
Subcellular
localization
wolf |
|
cyto_nucl 4,
cyto 4,
nucl 2,
extr 2,
mito 1,
pero 1,
mito_pero 1
|
(predict for NP_001342553.1)
|
|
cyto_nucl 4,
cyto 4,
nucl 2,
extr 2,
mito 1,
pero 1,
mito_pero 1
|
(predict for NP_062372.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu04110 |
Cell cycle |
3 |
 |
| mmu05200 |
Pathways in cancer |
2 |
 |
| mmu04114 |
Oocyte meiosis |
2 |
 |
| mmu04914 |
Progesterone-mediated oocyte maturation |
2 |
 |
Genes directly connected with Mad2l1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 12.7 |
Cip2a |
cell proliferation regulating inhibitor of protein phosphatase 2A |
[detail] |
0 |
224171 |
| 10.6 |
Rad51 |
RAD51 recombinase |
[detail] |
0 |
19361 |
| 10.5 |
Shcbp1 |
Shc SH2-domain binding protein 1 |
[detail] |
0 |
20419 |
| 10.3 |
Plk4 |
polo like kinase 4 |
[detail] |
3 |
20873 |
| 8.1 |
Gmnn |
geminin |
[detail] |
3 |
57441 |
| 7.9 |
Cenpq |
centromere protein Q |
[detail] |
0 |
83815 |
| 7.9 |
Cks1b |
CDC28 protein kinase 1b |
[detail] |
2 |
54124 |
| 7.6 |
Mis18a |
MIS18 kinetochore protein A |
[detail] |
0 |
66578 |
|
Coexpressed
gene list |
[Coexpressed gene list for Mad2l1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Mad2l1 Gene
