[←][→] mmu  Twnk Gene
functional annotation
Function   twinkle mtDNA helicase  
GO BP
GO:0034214 [list] [network] protein hexamerization  (9 genes)  ISO  
GO:0006264 [list] [network] mitochondrial DNA replication  (11 genes)  IBA IMP ISO  
GO:0006268 [list] [network] DNA unwinding involved in DNA replication  (14 genes)  IDA ISO  
GO:0006390 [list] [network] mitochondrial transcription  (14 genes)  ISO  
GO:0006260 [list] [network] DNA replication  (177 genes)  IEA  
GO CC
GO:0042645 [list] [network] mitochondrial nucleoid  (48 genes)  ISO  
GO:0005739 [list] [network] mitochondrion  (1890 genes)  HDA IBA IDA ISO  
GO MF
GO:0043139 [list] [network] 5'-3' DNA helicase activity  (9 genes)  ISO  
GO:0003678 [list] [network] DNA helicase activity  (69 genes)  IBA IDA ISA  
GO:0003697 [list] [network] single-stranded DNA binding  (116 genes)  IBA ISO  
GO:0004386 [list] [network] helicase activity  (151 genes)  IEA  
GO:0002020 [list] [network] protease binding  (183 genes)  ISO  
GO:0005524 [list] [network] ATP binding  (1396 genes)  IEA  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  ISO  
GO:0016787 [list] [network] hydrolase activity  (2400 genes)  IEA  
KEGG mmu05017 [list] [network] Spinocerebellar ataxia (141 genes)
Protein NP_001335183.1  NP_001335188.1  NP_722491.2 
BLAST NP_001335183.1  NP_001335188.1  NP_722491.2 
Orthologous [Ortholog page] mtDNA-helicase (dme)  TWNK (hsa)  twnk-1 (cel)  Twnk (rno)  C10orf2 (gga)  TWNK (cfa)  TWNK (mcc)  twnk (dre)  TWNK (fca) 
Subcellular
localization
wolf
cyto 7,  cyto_nucl 6,  nucl 3  (predict for NP_001335183.1)
mito 6,  cyto 3,  nucl 1,  pero 1  (predict for NP_001335188.1)
mito 5,  nucl 4,  cyto_mito 3,  mito_pero 3  (predict for NP_722491.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03008 Ribosome biogenesis in eukaryotes 3
Genes directly connected with Twnk on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.5 Eef1aknmt EEF1A lysine and N-terminal methyltransferase [detail] 0 71449
6.3 Tfb2m transcription factor B2, mitochondrial [detail] 0 15278
5.9 Polr1b polymerase (RNA) I polypeptide B [detail] 0 20017
Coexpressed
gene list		 [Coexpressed gene list for Twnk]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 226153      
Refseq ID (protein) NP_001335183.1 
NP_001335188.1 
NP_722491.2 


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