| functional annotation |
| Function |
stearoyl-Coenzyme A desaturase 1 |
|
| GO BP |
|
GO:1903699 [list] [network] tarsal gland development
|
(2 genes)
|
IMP
|
 |
|
GO:1903966 [list] [network] monounsaturated fatty acid biosynthetic process
|
(4 genes)
|
IBA
IDA
IGI
IMP
|
|
|
GO:0034434 [list] [network] sterol esterification
|
(5 genes)
|
IMP
|
|
|
GO:0034435 [list] [network] cholesterol esterification
|
(5 genes)
|
IMP
|
|
|
GO:0010873 [list] [network] positive regulation of cholesterol esterification
|
(10 genes)
|
TAS
|
|
|
GO:0048733 [list] [network] sebaceous gland development
|
(15 genes)
|
IMP
|
|
|
GO:0050872 [list] [network] white fat cell differentiation
|
(21 genes)
|
IDA
|
|
|
GO:0006636 [list] [network] unsaturated fatty acid biosynthetic process
|
(30 genes)
|
IBA
ISO
|
|
|
GO:0070542 [list] [network] response to fatty acid
|
(35 genes)
|
IBA
ISO
|
|
|
GO:0033561 [list] [network] regulation of water loss via skin
|
(37 genes)
|
IMP
|
|
|
GO:0050873 [list] [network] brown fat cell differentiation
|
(39 genes)
|
IDA
|
|
|
GO:0006641 [list] [network] triglyceride metabolic process
|
(72 genes)
|
IMP
|
|
|
GO:0120162 [list] [network] positive regulation of cold-induced thermogenesis
|
(97 genes)
|
IMP
|
|
|
GO:0006633 [list] [network] fatty acid biosynthetic process
|
(116 genes)
|
IMP
|
|
|
GO:0050830 [list] [network] defense response to Gram-positive bacterium
|
(154 genes)
|
IMP
|
|
|
GO:0055088 [list] [network] lipid homeostasis
|
(167 genes)
|
IMP
|
|
|
GO:0006631 [list] [network] fatty acid metabolic process
|
(366 genes)
|
IEA
|
|
|
GO:0008610 [list] [network] lipid biosynthetic process
|
(510 genes)
|
TAS
|
|
|
GO:0009617 [list] [network] response to bacterium
|
(978 genes)
|
IEP
|
|
|
GO:0006629 [list] [network] lipid metabolic process
|
(1148 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0030176 [list] [network] integral component of endoplasmic reticulum membrane
|
(153 genes)
|
IBA
IDA
|
|
|
GO:0005789 [list] [network] endoplasmic reticulum membrane
|
(613 genes)
|
IBA
ISO
|
|
|
GO:0005730 [list] [network] nucleolus
|
(895 genes)
|
ISO
|
|
|
GO:0005783 [list] [network] endoplasmic reticulum
|
(1825 genes)
|
ISO
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5954 genes)
|
ISO
|
|
|
GO:0016020 [list] [network] membrane
|
(9571 genes)
|
IEA
|
|
|
GO:0043231 [list] [network] intracellular membrane-bounded organelle
|
(11551 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0032896 [list] [network] palmitoyl-CoA 9-desaturase activity
|
(4 genes)
|
IBA
IDA
IGI
|
|
|
GO:0004768 [list] [network] stearoyl-CoA 9-desaturase activity
|
(6 genes)
|
IBA
IDA
IGI
ISO
|
|
|
GO:0016717 [list] [network] oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
|
(14 genes)
|
IEA
|
|
|
GO:0005506 [list] [network] iron ion binding
|
(171 genes)
|
IBA
ISO
|
|
|
GO:0016491 [list] [network] oxidoreductase activity
|
(801 genes)
|
ISO
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3573 genes)
|
IDA
|
|
|
| KEGG |
mmu01040 [list] [network] Biosynthesis of unsaturated fatty acids (34 genes) |
 |
| mmu01212 [list] [network] Fatty acid metabolism (62 genes) |
|
| mmu03320 [list] [network] PPAR signaling pathway (89 genes) |
|
| mmu04152 [list] [network] AMPK signaling pathway (126 genes) |
|
| mmu04936 [list] [network] Alcoholic liver disease (141 genes) |
|
| Protein |
NP_033153.2
|
| BLAST |
NP_033153.2
|
| Orthologous |
[Ortholog page]
SCD (hsa)
Scd2 (mmu)
Scd3 (mmu)
Desat2 (dme)
CG8630 (dme)
CG9747 (dme)
CG9743 (dme)
Fad2 (dme)
SCD5 (hsa)
Scd2 (rno)
Desat1 (dme)
fat-6 (cel)
fat-7 (cel)
fat-5 (cel)
Scd (rno)
Scd4 (mmu)
scd (dre)
SCD (gga)
SCD5 (gga)
SCD (cfa)
SCD5 (cfa)
Scd4 (rno)
scdb (dre)
LOC681458 (rno)
SCD5 (mcc)
SCD (mcc)
OLE1 (sce)
SCD5 (fca)
SCD (fca)
|
Subcellular
localization
wolf |
|
plas 9,
cyto 1
|
(predict for NP_033153.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu01212 |
Fatty acid metabolism |
9 |
 |
| mmu04152 |
AMPK signaling pathway |
7 |
 |
| mmu04936 |
Alcoholic liver disease |
7 |
 |
| mmu01040 |
Biosynthesis of unsaturated fatty acids |
7 |
 |
| mmu03320 |
PPAR signaling pathway |
5 |
 |
Genes directly connected with Scd1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 11.6 |
Fasn |
fatty acid synthase |
[detail] |
91 |
14104 |
| 10.9 |
Acaca |
acetyl-Coenzyme A carboxylase alpha |
[detail] |
77 |
107476 |
| 10.4 |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
[detail] |
48 |
20250 |
| 7.4 |
Me1 |
malic enzyme 1, NADP(+)-dependent, cytosolic |
[detail] |
17 |
17436 |
| 6.8 |
Elovl5 |
ELOVL family member 5, elongation of long chain fatty acids (yeast) |
[detail] |
29 |
68801 |
| 5.3 |
Scd3 |
stearoyl-coenzyme A desaturase 3 |
[detail] |
0 |
30049 |
| 5.1 |
H2-Q10 |
histocompatibility 2, Q region locus 10 |
[detail] |
0 |
15007 |
| 4.8 |
Car5b |
carbonic anhydrase 5b, mitochondrial |
[detail] |
0 |
56078 |
|
Coexpressed
gene list |
[Coexpressed gene list for Scd1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Scd1 Gene
