| functional annotation |
| Function |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 |
|
| GO BP |
|
GO:0043248 [list] [network] proteasome assembly
|
(14 genes)
|
IBA
|
 |
|
GO:0043161 [list] [network] proteasome-mediated ubiquitin-dependent protein catabolic process
|
(298 genes)
|
IBA
|
|
|
| GO CC |
|
GO:0008540 [list] [network] proteasome regulatory particle, base subcomplex
|
(12 genes)
|
IBA
|
|
|
GO:0022624 [list] [network] proteasome accessory complex
|
(25 genes)
|
IDA
|
|
|
GO:0000502 [list] [network] proteasome complex
|
(64 genes)
|
ISO
|
|
|
GO:0005654 [list] [network] nucleoplasm
|
(3580 genes)
|
ISO
|
|
|
GO:0005829 [list] [network] cytosol
|
(3785 genes)
|
IBA
ISO
|
|
|
GO:0005634 [list] [network] nucleus
|
(7226 genes)
|
IBA
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(11434 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0031593 [list] [network] polyubiquitin modification-dependent protein binding
|
(57 genes)
|
IBA
|
|
|
GO:0042802 [list] [network] identical protein binding
|
(2357 genes)
|
ISO
|
|
|
| KEGG |
mmu03050 [list] [network] Proteasome (47 genes) |
 |
| mmu05010 [list] [network] Alzheimer disease (383 genes) |
|
| mmu05012 [list] [network] Parkinson disease (264 genes) |
|
| mmu05014 [list] [network] Amyotrophic lateral sclerosis (369 genes) |
|
| mmu05016 [list] [network] Huntington disease (302 genes) |
|
| mmu05017 [list] [network] Spinocerebellar ataxia (141 genes) |
|
| mmu05020 [list] [network] Prion disease (268 genes) |
|
| mmu05022 [list] [network] Pathways of neurodegeneration - multiple diseases (471 genes) |
|
| mmu05169 [list] [network] Epstein-Barr virus infection (231 genes) |
|
| Protein |
NP_001268946.1
NP_032977.1
XP_006501200.1
XP_030108325.1
|
| BLAST |
NP_001268946.1
NP_032977.1
XP_006501200.1
XP_030108325.1
|
| Orthologous |
[Ortholog page]
PSMD4 (hsa)
Rpn10 (dme)
Psmd4 (rno)
rpn-10 (cel)
psmd4a (dre)
psmd4b (dre)
RPN10 (sce)
PSMD4 (cfa)
PSMD4 (mcc)
PSMD4 (gga)
PSMD4 (fca)
|
Subcellular
localization
wolf |
|
cysk 4,
cyto 4,
cyto_nucl 3,
nucl 2
|
(predict for NP_001268946.1)
|
|
cysk 5,
cyto 4,
cyto_nucl 3,
nucl 1
|
(predict for NP_032977.1)
|
|
cyto 7,
cyto_nucl 4,
nucl 1,
mito 1,
E.R._mito 1
|
(predict for XP_006501200.1)
|
|
cyto 7,
cyto_nucl 4,
nucl 1,
mito 1,
E.R._mito 1
|
(predict for XP_030108325.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu05014 |
Amyotrophic lateral sclerosis |
12 |
 |
| mmu05022 |
Pathways of neurodegeneration - multiple diseases |
12 |
 |
| mmu03050 |
Proteasome |
11 |
 |
| mmu05010 |
Alzheimer disease |
11 |
 |
| mmu05012 |
Parkinson disease |
11 |
 |
Genes directly connected with Psmd4 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 13.6 |
Psmc3 |
proteasome (prosome, macropain) 26S subunit, ATPase 3 |
[detail] |
1 |
19182 |
| 12.9 |
Psmc5 |
protease (prosome, macropain) 26S subunit, ATPase 5 |
[detail] |
2 |
19184 |
| 12.2 |
Psmc4 |
proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
[detail] |
3 |
23996 |
| 10.7 |
Nsfl1c |
NSFL1 (p97) cofactor (p47) |
[detail] |
0 |
386649 |
| 9.4 |
Psmd13 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
[detail] |
2 |
23997 |
| 8.5 |
Ubxn1 |
UBX domain protein 1 |
[detail] |
0 |
225896 |
| 7.6 |
Pak1ip1 |
PAK1 interacting protein 1 |
[detail] |
0 |
68083 |
| 7.6 |
Sqstm1 |
sequestosome 1 |
[detail] |
1 |
18412 |
| 7.2 |
Psmd8 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
[detail] |
2 |
57296 |
| 7.0 |
Rtf2 |
replication termination factor 2 |
[detail] |
0 |
66404 |
|
Coexpressed
gene list |
[Coexpressed gene list for Psmd4]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Psmd4 Gene
