COXPRESdb : GeneID search result

[←][→] mmu Dhcr7 Gene

functional annotation

Function

7-dehydrocholesterol reductase

GO BP

GO:0016132 [list] [network] brassinosteroid biosynthetic process	(1 genes)	IBA
GO:0045540 [list] [network] regulation of cholesterol biosynthetic process	(19 genes)	ISO
GO:0006695 [list] [network] cholesterol biosynthetic process	(40 genes)	IBA ISO
GO:0016126 [list] [network] sterol biosynthetic process	(46 genes)	IBA IMP
GO:0006694 [list] [network] steroid biosynthetic process	(105 genes)	IEA
GO:0008203 [list] [network] cholesterol metabolic process	(126 genes)	IEA
GO:0035264 [list] [network] multicellular organism growth	(132 genes)	IMP
GO:0009791 [list] [network] post-embryonic development	(134 genes)	IMP
GO:0030324 [list] [network] lung development	(226 genes)	IMP
GO:0008202 [list] [network] steroid metabolic process	(264 genes)	IEA
GO:0001568 [list] [network] blood vessel development	(547 genes)	IMP
GO:0006629 [list] [network] lipid metabolic process	(1148 genes)	IEA
GO:0042127 [list] [network] regulation of cell population proliferation	(1747 genes)	IMP
GO:0030154 [list] [network] cell differentiation	(3713 genes)	IMP

GO CC

GO:0005640 [list] [network] nuclear outer membrane	(19 genes)	ISO
GO:0030176 [list] [network] integral component of endoplasmic reticulum membrane	(153 genes)	IBA
GO:0005783 [list] [network] endoplasmic reticulum	(1825 genes)	ISO
GO:0016021 [list] [network] integral component of membrane	(5954 genes)	IEA
GO:0016020 [list] [network] membrane	(9571 genes)	IEA
GO:0043231 [list] [network] intracellular membrane-bounded organelle	(11551 genes)	ISO

GO MF

GO:0009918 [list] [network] sterol delta7 reductase activity	(1 genes)	IBA
GO:0047598 [list] [network] 7-dehydrocholesterol reductase activity	(1 genes)	IBA IDA ISO
GO:0016628 [list] [network] oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	(32 genes)	IEA
GO:0016627 [list] [network] oxidoreductase activity, acting on the CH-CH group of donors	(65 genes)	IBA
GO:0016491 [list] [network] oxidoreductase activity	(801 genes)	IEA

KEGG

mmu00100 [list] [network] Steroid biosynthesis (20 genes)

Protein

NP_001369427.1 NP_001369428.1 NP_001369429.1 NP_001369430.1 NP_001369431.1 NP_001369432.1 NP_031882.1 XP_006508539.2 XP_006508541.1 XP_011240281.1 XP_030097935.1 XP_030097936.1 XP_036008526.1 XP_036008527.1 XP_036008528.1 XP_036008529.1 XP_036008530.1 XP_036008531.1 XP_036008532.1

BLAST

Orthologous

[Ortholog page] DHCR7 (hsa) LBR (hsa) TM7SF2 (hsa) LBR (dme) Dhcr7 (rno) Tm7sf2 (mmu) Lbr (rno) Lbr (mmu) dhcr-7 (cel) Tm7sf2 (rno) lbr (dre) dhcr7 (dre) LBR (gga) DHCR7 (gga) TM7SF2 (cfa) DHCR7 (cfa) LBR (cfa) tm7sf2 (dre) LBR (mcc) TM7SF2 (mcc) ERG4 (sce) ERG24 (sce) si:ch1073-429i10.1 (dre) TM7SF2 (fca) LBR (fca) DHCR7 (fca) DHCR7 (mcc)

Subcellular
localization
wolf

plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for NP_001369427.1)
cyto_nucl 4, cyto 4, nucl 3, mito 1	(predict for NP_001369428.1)
cyto 6, cyto_nucl 4, cyto_plas 3, extr 2, nucl 1	(predict for NP_001369429.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for NP_001369430.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for NP_001369431.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for NP_001369432.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for NP_031882.1)
plas 6, extr_plas 4, extr 1, cyto 1, mito 1, E.R. 1, lyso 1, E.R._mito 1, cyto_mito 1	(predict for XP_006508539.2)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for XP_006508541.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for XP_011240281.1)
mito 4, nucl 3, E.R._mito 3	(predict for XP_030097935.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for XP_030097936.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for XP_036008526.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for XP_036008527.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for XP_036008528.1)
plas 6, E.R. 2, cyto 1, E.R._golg 1	(predict for XP_036008529.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for XP_036008530.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for XP_036008531.1)
cyto 3, cyto_nucl 3, cyto_pero 3, mito 2, nucl 2, pero 1	(predict for XP_036008532.1)

Gene coexpression

Network^*for
coexpressed
genes

[Cytoscape]

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mmu00100	Steroid biosynthesis	8
mmu00900	Terpenoid backbone biosynthesis	6
mmu04976	Bile secretion	3
mmu04913	Ovarian steroidogenesis	2
mmu04925	Aldosterone synthesis and secretion	2

Genes directly connected with Dhcr7 on the network
coex z^*	Locus	Function^*	Coexpression detail	CoexPub	Entrez Gene ID^*
16.1	Nsdhl	NAD(P) dependent steroid dehydrogenase-like	[detail]	11	18194
15.0	Msmo1	methylsterol monoxygenase 1	[detail]	6	66234
14.9	Cyp51	cytochrome P450, family 51	[detail]	14	13121
5.5	Mfsd13a	major facilitator superfamily domain containing 13a	[detail]	0	75146
5.3	Mblac2	metallo-beta-lactamase domain containing 2	[detail]	0	72852
5.1	Zdhhc9	zinc finger, DHHC domain containing 9	[detail]	0	208884
4.2	Scarb1	scavenger receptor class B, member 1	[detail]	0	20778

Coexpressed
gene list

[Coexpressed gene list for Dhcr7]

Gene expression

All samples

[Expression pattern for all samples]

Tissue specificity^*

Link to other DBs
Entrez Gene ID	13360
Refseq ID (protein)	NP_001369427.1
	NP_001369428.1
	NP_001369429.1
	NP_001369430.1
	NP_001369431.1
	NP_001369432.1
	NP_031882.1
	XP_006508539.2
	XP_006508541.1
	XP_011240281.1
	XP_030097935.1
	XP_030097936.1
	XP_036008526.1
	XP_036008527.1
	XP_036008528.1
	XP_036008529.1
	XP_036008530.1
	XP_036008531.1
	XP_036008532.1

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