[←][→] mmu  Ctsl Gene
functional annotation
Function   cathepsin L  
GO BP
GO:0060309 [list] [network] elastin catabolic process  (3 genes)  IMP  
GO:0042637 [list] [network] catagen  (4 genes)  IMP  
GO:0039654 [list] [network] fusion of virus membrane with host endosome membrane  (12 genes)  ISO  
GO:0006590 [list] [network] thyroid hormone generation  (13 genes)  IMP  
GO:0010839 [list] [network] negative regulation of keratinocyte proliferation  (15 genes)  IMP  
GO:0019064 [list] [network] fusion of virus membrane with host plasma membrane  (15 genes)  ISO  
GO:0043373 [list] [network] CD4-positive, alpha-beta T cell lineage commitment  (16 genes)  IMP  
GO:0019065 [list] [network] receptor-mediated endocytosis of virus by host cell  (19 genes)  ISO  
GO:0046697 [list] [network] decidualization  (21 genes)  IGI  
GO:0060441 [list] [network] epithelial tube branching involved in lung morphogenesis  (34 genes)  IMP  
GO:0016540 [list] [network] protein autoprocessing  (36 genes)  IDA ISO  
GO:0031069 [list] [network] hair follicle morphogenesis  (37 genes)  IMP  
GO:2000249 [list] [network] regulation of actin cytoskeleton reorganization  (39 genes)  IGI  
GO:0030574 [list] [network] collagen catabolic process  (43 genes)  IDA ISO  
GO:0046718 [list] [network] viral entry into host cell  (57 genes)  ISO  
GO:0048002 [list] [network] antigen processing and presentation of peptide antigen  (70 genes)  IMP  
GO:0031638 [list] [network] zymogen activation  (73 genes)  ISO  
GO:0016485 [list] [network] protein processing  (195 genes)  IDA IMP  
GO:0051603 [list] [network] proteolysis involved in cellular protein catabolic process  (594 genes)  IBA IMP ISO  
GO:0006508 [list] [network] proteolysis  (1144 genes)  IDA ISO  
GO:0006955 [list] [network] immune response  (1640 genes)  IBA  
GO:0007154 [list] [network] cell communication  (5404 genes)  ISO  
GO CC
GO:0005771 [list] [network] multivesicular body  (66 genes)  ISO  
GO:0005902 [list] [network] microvillus  (103 genes)  ISO  
GO:0043204 [list] [network] perikaryon  (139 genes)  ISO  
GO:0062023 [list] [network] collagen-containing extracellular matrix  (392 genes)  HDA  
GO:0030141 [list] [network] secretory granule  (431 genes)  ISO  
GO:0045177 [list] [network] apical part of cell  (483 genes)  ISO  
GO:0005764 [list] [network] lysosome  (520 genes)  IBA IDA ISO  
GO:0005773 [list] [network] vacuole  (615 genes)  ISO  
GO:0009897 [list] [network] external side of plasma membrane  (621 genes)  IDA ISO  
GO:0005730 [list] [network] nucleolus  (895 genes)  IDA  
GO:0005794 [list] [network] Golgi apparatus  (1525 genes)  ISO  
GO:0043005 [list] [network] neuron projection  (1541 genes)  ISO  
GO:0005615 [list] [network] extracellular space  (2015 genes)  IBA IDA ISO  
GO:0031410 [list] [network] cytoplasmic vesicle  (2033 genes)  IDA  
GO:0005576 [list] [network] extracellular region  (2754 genes)  IEA  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO  
GO:0005634 [list] [network] nucleus  (7226 genes)  IDA  
GO:0016020 [list] [network] membrane  (9571 genes)  IEA  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  ISO  
GO:0043231 [list] [network] intracellular membrane-bounded organelle  (11551 genes)  ISO  
GO MF
GO:0016807 [list] [network] cysteine-type carboxypeptidase activity  (3 genes)  IDA  
GO:0030984 [list] [network] kininogen binding  (4 genes)  ISO  
GO:0097655 [list] [network] serpin family protein binding  (12 genes)  ISO  
GO:0004177 [list] [network] aminopeptidase activity  (36 genes)  ISO  
GO:0001968 [list] [network] fibronectin binding  (45 genes)  ISO  
GO:0043394 [list] [network] proteoglycan binding  (55 genes)  ISO  
GO:0005518 [list] [network] collagen binding  (80 genes)  ISO  
GO:0004197 [list] [network] cysteine-type endopeptidase activity  (101 genes)  IBA ISO  
GO:0008234 [list] [network] cysteine-type peptidase activity  (183 genes)  ISO  
GO:0042393 [list] [network] histone binding  (286 genes)  IDA ISO  
GO:0042277 [list] [network] peptide binding  (370 genes)  ISO  
GO:0004175 [list] [network] endopeptidase activity  (449 genes)  IMP  
GO:0008233 [list] [network] peptidase activity  (649 genes)  IEA  
GO:0044877 [list] [network] protein-containing complex binding  (1549 genes)  ISO  
GO:0016787 [list] [network] hydrolase activity  (2400 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04140 [list] [network] Autophagy - animal (142 genes)
mmu04142 [list] [network] Lysosome (135 genes)
mmu04145 [list] [network] Phagosome (182 genes)
mmu04210 [list] [network] Apoptosis (136 genes)
mmu04612 [list] [network] Antigen processing and presentation (90 genes)
mmu05205 [list] [network] Proteoglycans in cancer (205 genes)
mmu05323 [list] [network] Rheumatoid arthritis (87 genes)
mmu05418 [list] [network] Fluid shear stress and atherosclerosis (148 genes)
Protein NP_034114.1  XP_006517143.1 
BLAST NP_034114.1  XP_006517143.1 
Orthologous [Ortholog page] CTSL (hsa)  CTSV (hsa)  Ctsl (rno)  ctslb (dre)  Cp1 (dme)  cpl-1 (cel)  ctsla (dre)  si:dkey-239j18.2 (dre)  CTSV (gga)  ctsl.1 (dre)  ctsll (dre)  CTSL3 (cfa)  si:dkey-26g8.5 (dre)  si:dkey-269i1.4 (dre)  MGC174155 (dre)  wu:fa26c03 (dre)  zgc:174153 (dre)  zgc:174855 (dre)  CTSL (mcc)  LOC707167 (mcc)  CTSV (mcc)  PDP (fca)  si:dkey-239j18.3 (dre)  LOC100536033 (dre)  zgc:174154 (dre)  si:dkey-26g8.4 (dre)  LOC100688895 (cfa)  LOC101082639 (fca)  LOC101082891 (fca)  LOC101086605 (fca)  LOC101087880 (fca)  LOC101101202 (fca)  CTSV (cfa)  LOC105259631 (fca)  LOC111559122 (fca) 
Subcellular
localization
wolf
extr 8,  lyso 1  (predict for NP_034114.1)
extr 8,  lyso 1  (predict for XP_006517143.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04142 Lysosome 11
mmu04210 Apoptosis 4
mmu04140 Autophagy - animal 4
mmu04612 Antigen processing and presentation 3
mmu04145 Phagosome 2
Genes directly connected with Ctsl on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
8.5 Ctsb cathepsin B [detail] 65 13030
7.9 Cdk20 cyclin-dependent kinase 20 [detail] 1 105278
7.3 Lgmn legumain [detail] 11 19141
5.8 Prxl2c peroxiredoxin like 2C [detail] 0 66129
Coexpressed
gene list		 [Coexpressed gene list for Ctsl]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 13039      
Refseq ID (protein) NP_034114.1 
XP_006517143.1 


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