[←][→] mmu  B2m Gene
functional annotation
Function   beta-2 microglobulin  
GO BP
GO:0071283 [list] [network] cellular response to iron(III) ion  (2 genes)  IMP  
GO:1904434 [list] [network] positive regulation of ferrous iron binding  (2 genes)  ISO  
GO:1904437 [list] [network] positive regulation of transferrin receptor binding  (2 genes)  ISO  
GO:0002481 [list] [network] antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent  (3 genes)  IMP  
GO:2000978 [list] [network] negative regulation of forebrain neuron differentiation  (4 genes)  IMP ISO  
GO:0071316 [list] [network] cellular response to nicotine  (6 genes)  ISO  
GO:1900122 [list] [network] positive regulation of receptor binding  (8 genes)  ISO  
GO:0090647 [list] [network] modulation of age-related behavioral decline  (10 genes)  IMP ISO  
GO:1990000 [list] [network] amyloid fibril formation  (10 genes)  ISO  
GO:0002503 [list] [network] peptide antigen assembly with MHC class II protein complex  (11 genes)  IBA  
GO:0071281 [list] [network] cellular response to iron ion  (12 genes)  ISO  
GO:1900121 [list] [network] negative regulation of receptor binding  (13 genes)  ISO  
GO:2000774 [list] [network] positive regulation of cellular senescence  (13 genes)  ISO  
GO:0034756 [list] [network] regulation of iron ion transport  (14 genes)  ISO  
GO:0006968 [list] [network] cellular defense response  (15 genes)  TAS  
GO:0042026 [list] [network] protein refolding  (15 genes)  IDA  
GO:0019886 [list] [network] antigen processing and presentation of exogenous peptide antigen via MHC class II  (20 genes)  IBA  
GO:0002726 [list] [network] positive regulation of T cell cytokine production  (25 genes)  ISO  
GO:0019885 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class I  (40 genes)  ISO  
GO:0002381 [list] [network] immunoglobulin production involved in immunoglobulin-mediated immune response  (43 genes)  IBA  
GO:0002474 [list] [network] antigen processing and presentation of peptide antigen via MHC class I  (49 genes)  IEA  
GO:0003254 [list] [network] regulation of membrane depolarization  (49 genes)  ISO  
GO:0006826 [list] [network] iron ion transport  (50 genes)  IMP  
GO:0045646 [list] [network] regulation of erythrocyte differentiation  (50 genes)  IMP  
GO:0001916 [list] [network] positive regulation of T cell mediated cytotoxicity  (51 genes)  IMP  
GO:0051289 [list] [network] protein homotetramerization  (51 genes)  ISO  
GO:0048260 [list] [network] positive regulation of receptor-mediated endocytosis  (63 genes)  ISO  
GO:0033077 [list] [network] T cell differentiation in thymus  (66 genes)  IGI  
GO:0055072 [list] [network] iron ion homeostasis  (92 genes)  IMP  
GO:0019731 [list] [network] antibacterial humoral response  (93 genes)  ISO  
GO:0032092 [list] [network] positive regulation of protein binding  (99 genes)  ISO  
GO:0061844 [list] [network] antimicrobial humoral immune response mediated by antimicrobial peptide  (126 genes)  ISO  
GO:0050829 [list] [network] defense response to Gram-negative bacterium  (129 genes)  ISO  
GO:0050830 [list] [network] defense response to Gram-positive bacterium  (154 genes)  ISO  
GO:0010977 [list] [network] negative regulation of neuron projection development  (162 genes)  IGI  
GO:0050768 [list] [network] negative regulation of neurogenesis  (162 genes)  IMP ISO  
GO:0050680 [list] [network] negative regulation of epithelial cell proliferation  (171 genes)  ISO  
GO:0050870 [list] [network] positive regulation of T cell activation  (221 genes)  IBA  
GO:0071222 [list] [network] cellular response to lipopolysaccharide  (281 genes)  ISO  
GO:0007611 [list] [network] learning or memory  (314 genes)  IMP ISO  
GO:0002237 [list] [network] response to molecule of bacterial origin  (391 genes)  IMP  
GO:0045087 [list] [network] innate immune response  (814 genes)  ISO  
GO:0006955 [list] [network] immune response  (1640 genes)  IEA  
GO:0002376 [list] [network] immune system process  (2502 genes)  IEA  
GO:0007275 [list] [network] multicellular organism development  (5017 genes)  IMP  
GO CC
GO:1990712 [list] [network] HFE-transferrin receptor complex  (6 genes)  ISO  
GO:0042824 [list] [network] MHC class I peptide loading complex  (11 genes)  ISO  
GO:0042613 [list] [network] MHC class II protein complex  (12 genes)  IBA  
GO:0042612 [list] [network] MHC class I protein complex  (26 genes)  IEA  
GO:0030670 [list] [network] phagocytic vesicle membrane  (27 genes)  TAS  
GO:0009897 [list] [network] external side of plasma membrane  (621 genes)  IDA  
GO:0005794 [list] [network] Golgi apparatus  (1525 genes)  ISO  
GO:0005615 [list] [network] extracellular space  (2015 genes)  HDA ISO  
GO:0005576 [list] [network] extracellular region  (2754 genes)  IEA  
GO:0005829 [list] [network] cytosol  (3785 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO  
GO MF
GO:0023026 [list] [network] MHC class II protein complex binding  (13 genes)  IBA  
GO:0042803 [list] [network] protein homodimerization activity  (780 genes)  ISO  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  ISO  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04612 [list] [network] Antigen processing and presentation (90 genes)
mmu05163 [list] [network] Human cytomegalovirus infection (256 genes)
mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes)
mmu05168 [list] [network] Herpes simplex virus 1 infection (459 genes)
mmu05169 [list] [network] Epstein-Barr virus infection (231 genes)
mmu05170 [list] [network] Human immunodeficiency virus 1 infection (240 genes)
Protein NP_033865.2 
BLAST NP_033865.2 
Orthologous [Ortholog page] B2M (hsa)  B2m (rno)  b2m (dre)  B2M (gga)  B2M (fca)  B2M (mcc)  b2ml (dre)  B2M (cfa) 
Subcellular
localization
wolf
extr 9  (predict for NP_033865.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04612 Antigen processing and presentation 14
mmu05168 Herpes simplex virus 1 infection 14
mmu05169 Epstein-Barr virus infection 14
mmu04145 Phagosome 13
mmu05163 Human cytomegalovirus infection 13
Genes directly connected with B2m on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
15.2 H2-D1 histocompatibility 2, D region locus 1 [detail] 5 14964
14.2 H2-K1 histocompatibility 2, K1, K region [detail] 28 14972
10.1 H2-Q4 histocompatibility 2, Q region locus 4 [detail] 0 15015
Coexpressed
gene list		 [Coexpressed gene list for B2m]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 12010      
Refseq ID (protein) NP_033865.2 


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