[←][→] mmu  Parp1 Gene
functional annotation
Function   poly (ADP-ribose) polymerase family, member 1  
GO BP
GO:0018424 [list] [network] peptidyl-glutamic acid poly-ADP-ribosylation  (1 genes)  ISO  
GO:1904762 [list] [network] positive regulation of myofibroblast differentiation  (1 genes)  ISO  
GO:1903516 [list] [network] regulation of single strand break repair  (2 genes)  IMP  
GO:1903518 [list] [network] positive regulation of single strand break repair  (2 genes)  IGI ISO  
GO:0018312 [list] [network] peptidyl-serine ADP-ribosylation  (3 genes)  ISO  
GO:0030592 [list] [network] DNA ADP-ribosylation  (3 genes)  ISO  
GO:1990966 [list] [network] ATP generation from poly-ADP-D-ribose  (4 genes)  ISO  
GO:2001170 [list] [network] negative regulation of ATP biosynthetic process  (4 genes)  ISO  
GO:0010990 [list] [network] regulation of SMAD protein complex assembly  (6 genes)  ISO  
GO:0043504 [list] [network] mitochondrial DNA repair  (6 genes)  ISO  
GO:0042769 [list] [network] DNA damage response, detection of DNA damage  (8 genes)  ISO  
GO:0070212 [list] [network] protein poly-ADP-ribosylation  (8 genes)  IBA IDA ISO  
GO:0050882 [list] [network] voluntary musculoskeletal movement  (9 genes)  IGI  
GO:0040009 [list] [network] regulation of growth rate  (10 genes)  IMP  
GO:1903376 [list] [network] regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (10 genes)  ISO  
GO:0032042 [list] [network] mitochondrial DNA metabolic process  (11 genes)  ISO  
GO:0051901 [list] [network] positive regulation of mitochondrial depolarization  (11 genes)  ISO  
GO:0070213 [list] [network] protein auto-ADP-ribosylation  (12 genes)  ISO  
GO:0033148 [list] [network] positive regulation of intracellular estrogen receptor signaling pathway  (13 genes)  ISO  
GO:0071451 [list] [network] cellular response to superoxide  (14 genes)  IDA  
GO:0060391 [list] [network] positive regulation of SMAD protein signal transduction  (15 genes)  ISO  
GO:1905168 [list] [network] positive regulation of double-strand break repair via homologous recombination  (16 genes)  ISO  
GO:0032700 [list] [network] negative regulation of interleukin-17 production  (19 genes)  IMP  
GO:0048148 [list] [network] behavioral response to cocaine  (20 genes)  IMP  
GO:1904357 [list] [network] negative regulation of telomere maintenance via telomere lengthening  (25 genes)  IMP  
GO:2000679 [list] [network] positive regulation of transcription regulatory region DNA binding  (25 genes)  ISO  
GO:0006471 [list] [network] protein ADP-ribosylation  (27 genes)  ISO  
GO:0023019 [list] [network] signal transduction involved in regulation of gene expression  (27 genes)  ISO  
GO:0044030 [list] [network] regulation of DNA methylation  (31 genes)  ISO  
GO:1904646 [list] [network] cellular response to amyloid-beta  (33 genes)  ISO  
GO:0016540 [list] [network] protein autoprocessing  (36 genes)  ISO  
GO:0006284 [list] [network] base-excision repair  (38 genes)  IMP  
GO:0010613 [list] [network] positive regulation of cardiac muscle hypertrophy  (41 genes)  ISO  
GO:0000723 [list] [network] telomere maintenance  (77 genes)  IMP  
GO:0007179 [list] [network] transforming growth factor beta receptor signaling pathway  (87 genes)  ISO  
GO:0034644 [list] [network] cellular response to UV  (89 genes)  ISO  
GO:1900182 [list] [network] positive regulation of protein localization to nucleus  (92 genes)  ISO  
GO:0071560 [list] [network] cellular response to transforming growth factor beta stimulus  (128 genes)  ISO  
GO:1901216 [list] [network] positive regulation of neuron death  (129 genes)  ISO  
GO:0032869 [list] [network] cellular response to insulin stimulus  (138 genes)  ISO  
GO:0006302 [list] [network] double-strand break repair  (182 genes)  IBA IGI ISO  
GO:0034599 [list] [network] cellular response to oxidative stress  (203 genes)  ISO  
GO:0007005 [list] [network] mitochondrion organization  (429 genes)  IMP ISO  
GO:0006281 [list] [network] DNA repair  (450 genes)  TAS  
GO:1903827 [list] [network] regulation of cellular protein localization  (562 genes)  ISO  
GO:0006259 [list] [network] DNA metabolic process  (654 genes)  IMP  
GO:0006974 [list] [network] cellular response to DNA damage stimulus  (691 genes)  ISO  
GO:0006915 [list] [network] apoptotic process  (831 genes)  ISO  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (1250 genes)  ISO  
GO:0050790 [list] [network] regulation of catalytic activity  (1819 genes)  ISO  
GO:0036211 [list] [network] protein modification process  (2289 genes)  ISO  
GO CC
GO:0035861 [list] [network] site of double-strand break  (63 genes)  ISO  
GO:0090734 [list] [network] site of DNA damage  (88 genes)  ISO  
GO:0032993 [list] [network] protein-DNA complex  (163 genes)  ISO  
GO:0005635 [list] [network] nuclear envelope  (421 genes)  ISO  
GO:0005667 [list] [network] transcription regulator complex  (474 genes)  ISO  
GO:0016604 [list] [network] nuclear body  (732 genes)  ISO  
GO:0005730 [list] [network] nucleolus  (895 genes)  IBA IDA ISO  
GO:0005694 [list] [network] chromosome  (1189 genes)  IEA  
GO:0005739 [list] [network] mitochondrion  (1890 genes)  ISO  
GO:0005654 [list] [network] nucleoplasm  (3580 genes)  IDA ISO  
GO:0032991 [list] [network] protein-containing complex  (5540 genes)  IDA ISO  
GO:0005634 [list] [network] nucleus  (7226 genes)  IDA ISO TAS  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IDA ISO  
GO MF
GO:0140294 [list] [network] NAD DNA ADP-ribosyltransferase activity  (3 genes)  ISO  
GO:1990404 [list] [network] protein ADP-ribosylase activity  (15 genes)  IBA IDA ISO  
GO:0003950 [list] [network] NAD+ ADP-ribosyltransferase activity  (24 genes)  IBA IDA IMP ISO  
GO:0070412 [list] [network] R-SMAD binding  (24 genes)  ISO  
GO:0030331 [list] [network] estrogen receptor binding  (50 genes)  ISO  
GO:0051287 [list] [network] NAD binding  (63 genes)  ISO  
GO:0046332 [list] [network] SMAD binding  (85 genes)  ISO  
GO:0042826 [list] [network] histone deacetylase binding  (130 genes)  ISO  
GO:0047485 [list] [network] protein N-terminus binding  (131 genes)  ISO  
GO:0016757 [list] [network] glycosyltransferase activity  (270 genes)  IEA  
GO:0003682 [list] [network] chromatin binding  (648 genes)  IDA  
GO:0008134 [list] [network] transcription factor binding  (673 genes)  ISO  
GO:0008270 [list] [network] zinc ion binding  (700 genes)  IEA  
GO:0019901 [list] [network] protein kinase binding  (774 genes)  ISO  
GO:0016740 [list] [network] transferase activity  (2235 genes)  IEA  
GO:0019899 [list] [network] enzyme binding  (2298 genes)  ISO  
GO:0003677 [list] [network] DNA binding  (2338 genes)  IEA  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  ISO  
GO:0046872 [list] [network] metal ion binding  (3573 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu03410 [list] [network] Base excision repair (36 genes)
mmu04064 [list] [network] NF-kappa B signaling pathway (105 genes)
mmu04210 [list] [network] Apoptosis (136 genes)
mmu04217 [list] [network] Necroptosis (176 genes)
mmu05415 [list] [network] Diabetic cardiomyopathy (211 genes)
Protein NP_031441.2 
BLAST NP_031441.2 
Orthologous [Ortholog page] PARP1 (hsa)  Parp1 (rno)  parp-1 (cel)  PARP1 (gga)  PARP1 (cfa)  parp1 (dre)  PARP1 (mcc)  Parp (dme)  PARP1 (fca) 
Subcellular
localization
wolf
nucl 10  (predict for NP_031441.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu03040 Spliceosome 3
mmu00240 Pyrimidine metabolism 3
mmu01240 Biosynthesis of cofactors 3
mmu03030 DNA replication 3
mmu03430 Mismatch repair 2
Genes directly connected with Parp1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.6 Gart phosphoribosylglycinamide formyltransferase [detail] 0 14450
6.4 Eftud2 elongation factor Tu GTP binding domain containing 2 [detail] 1 20624
6.4 Rpa1 replication protein A1 [detail] 2 68275
5.7 Gga2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 [detail] 0 74105
Coexpressed
gene list		 [Coexpressed gene list for Parp1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 11545      
Refseq ID (protein) NP_031441.2 


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