| functional annotation |
| Function |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
|
| GO BP |
|
GO:0046452 [list] [network] dihydrofolate metabolic process
|
(2 genes)
|
ISO
|
 |
|
GO:0006189 [list] [network] 'de novo' IMP biosynthetic process
|
(4 genes)
|
IBA
ISO
|
|
|
GO:0046654 [list] [network] tetrahydrofolate biosynthetic process
|
(6 genes)
|
ISO
|
|
|
GO:0098761 [list] [network] cellular response to interleukin-7
|
(17 genes)
|
IDA
|
|
|
GO:0009116 [list] [network] nucleoside metabolic process
|
(53 genes)
|
ISO
|
|
|
GO:0006164 [list] [network] purine nucleotide biosynthetic process
|
(129 genes)
|
IEA
|
|
|
GO:0009259 [list] [network] ribonucleotide metabolic process
|
(299 genes)
|
ISO
|
|
|
GO:0008152 [list] [network] metabolic process
|
(7626 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0003937 [list] [network] IMP cyclohydrolase activity
|
(1 genes)
|
IBA
ISO
|
|
|
GO:0004643 [list] [network] phosphoribosylaminoimidazolecarboxamide formyltransferase activity
|
(1 genes)
|
IBA
ISO
|
|
|
GO:0042803 [list] [network] protein homodimerization activity
|
(780 genes)
|
ISO
|
|
|
GO:0016740 [list] [network] transferase activity
|
(2235 genes)
|
IEA
|
|
|
GO:0016787 [list] [network] hydrolase activity
|
(2400 genes)
|
IEA
|
|
|
GO:0003824 [list] [network] catalytic activity
|
(5635 genes)
|
IEA
|
|
|
| KEGG |
mmu00230 [list] [network] Purine metabolism (133 genes) |
 |
| mmu00670 [list] [network] One carbon pool by folate (19 genes) |
|
| mmu01523 [list] [network] Antifolate resistance (29 genes) |
|
| Protein |
NP_080471.2
|
| BLAST |
NP_080471.2
|
| Orthologous |
[Ortholog page]
ATIC (hsa)
CG11089 (dme)
Atic (rno)
atic (dre)
atic-1 (cel)
ATIC (gga)
ATIC (cfa)
ATIC (mcc)
ADE16 (sce)
ADE17 (sce)
ATIC (fca)
|
Subcellular
localization
wolf |
|
cyto 6,
cyto_nucl 5,
nucl 3,
extr 1
|
(predict for NP_080471.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu00230 |
Purine metabolism |
2 |
 |
| mmu00670 |
One carbon pool by folate |
2 |
 |
| mmu01523 |
Antifolate resistance |
2 |
 |
Genes directly connected with Atic on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 9.3 |
Mybbp1a |
MYB binding protein (P160) 1a |
[detail] |
0 |
18432 |
| 9.1 |
Pa2g4 |
proliferation-associated 2G4 |
[detail] |
0 |
18813 |
| 8.7 |
Eif4g1 |
eukaryotic translation initiation factor 4, gamma 1 |
[detail] |
0 |
208643 |
| 7.4 |
Trp53 |
transformation related protein 53 |
[detail] |
0 |
22059 |
| 6.0 |
Mtap |
methylthioadenosine phosphorylase |
[detail] |
0 |
66902 |
|
Coexpressed
gene list |
[Coexpressed gene list for Atic]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Atic Gene
