COXPRESdb

ver. 6.0



Cfa: TOP2A External Links; ncbi pubmed
Orthologous gene group in HomoloGene**
Hsa genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Hsa2 genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Hsa3 genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Mcc genes
TOP2A ☆☆☆ DNA topoisomerase 2-alpha-like
Mmu genes
Top2a ☆☆☆ topoisomerase (DNA) II alpha
Mmu2 genes
Top2a ☆☆☆ topoisomerase (DNA) II alpha
Rno genes
Top2a ☆☆☆ topoisomerase (DNA) II alpha
Gga genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Dre genes
top2a topoisomerase (DNA) II alpha
Dme genes
Top2 ☆☆☆ Topoisomerase 2
Dme2 genes
Top2 Topoisomerase 2
Cel genes
top-2 ☆☆ Protein TOP-2


Top 100 coexpressed genes to TOP2A (Cfa c2.0 coexpression data)


Row filter: Column filter:
  Gene Function Entrez Gene ID Supportability* Cfa
Cfa MR*
for
TOP2A
 
Hsa
Hsa MR*
for
TOP2A
[list]
☆☆☆
Hsa2
Hsa2 MR*
for
TOP2A
[list]
☆☆☆
Hsa3
Hsa3 MR*
for
TOP2A
[list]
☆☆☆
Mcc
Mcc MR*
for
TOP2A
[list]
☆☆☆
Mmu
Mmu MR*
for
Top2a
[list]
☆☆☆
Mmu2
Mmu2 MR*
for
Top2a
[list]
☆☆☆
Rno
Rno MR*
for
Top2a
[list]
☆☆☆
Gga
Gga MR*
for
TOP2A
[list]
☆☆☆
Dre
Dre MR*
for
top2a
[list]
 
Dme
Dme MR*
for
Top2
[list]
☆☆☆
Dme2
Dme2 MR*
for
Top2
[list]
 
Cel
Cel MR*
for
top-2
[list]
☆☆
0 TOP2A topoisomerase (DNA) II alpha 170kDa 480525 ☆☆☆ 0.0 0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
1 KIF11 kinesin family member 11 477769 ☆☆☆ 1.0 2.8
1.4
6.0
18.7
2.5
13.0
27.6
792.6
26.9
22.4
2 CENPF centromere protein F, 350/400kDa (mitosin) 480027 ☆☆☆ 1.4 4.9
3.5
1.4
15.7
8.3
11.2
112.5
3 ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 480009 ☆☆☆ 2.8 1.4
3.0
1.7
18.6
19.1
3.0
14.1
165.7
4 TTK TTK protein kinase 481895 ☆☆☆ 3.0 12.7
16.0
8.1
34.6
14.9
4.8
91.6
337.4
5 NCAPG non-SMC condensin I complex, subunit G 479132 ☆☆☆ 3.5 14.3
2.8
3.2
2.0
8.9
7.9
36.1
1032.8
72.8
6 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 608350 ☆☆☆ 3.9 7.3
8.8
4.6
16.2
6.8
10.1
10.0
274.2
7 CDK1 cyclin-dependent kinase 1 488997 4.5
8 NCAPH non-SMC condensin I complex, subunit H 475741 ☆☆☆ 4.6 42.2
23.9
33.0
17.2
4.9
163.3
43.3
194.3
9 TPX2 TPX2, microtubule-associated 477186 ☆☆☆ 4.9 5.0
2.2
2.0
9.7
20.8
3.9
22.2
10 DEPDC1B DEP domain containing 1B 608968 ☆☆☆ 6.0 34.6
32.5
23.8
93.2
36.1
22.8
160.0
11 DLGAP5 discs, large (Drosophila) homolog-associated protein 5 480331 ☆☆☆ 6.5 4.6
1.0
3.9
7.1
62.6
16.9
18.0
54.5
97.3
12 CCNA2 cyclin A2 483845 ☆☆☆ 7.0 29.1
10.9
18.7
6.3
3.5
17.8
8.9
59.6
1472.3
103.8
29.8
13 478498   478498 7.6
14 KIF15 kinesin family member 15 476656 ☆☆☆ 8.2 17.0
25.8
9.6
4438.3
9.6
41.8
29.7
104.9
15 CKAP2 cytoskeleton associated protein 2 477291 ☆☆☆ 8.4 34.9
13.5
39.0
9.2
25.0
10.8
15.5
56.2
1680.2
16 CASC5 cancer susceptibility candidate 5 478260 ☆☆☆ 9.5 17.2
6.7
16.7
104.8
4.5
3229.0
17 ARHGAP11A Rho GTPase activating protein 11A 487476 ☆☆☆ 9.8 125.9
12.0
58.6
11.6
21.1
13.0
69.2
1568.2
18 NUF2 NUF2, NDC80 kinetochore complex component 478988 ☆☆☆ 9.9 9.4
8.8
13.5
3.0
17.9
44.9
12.0
41.8
459.1
19 NUSAP1 nucleolar and spindle associated protein 1 475154 ☆☆☆ 10.2 4.6
3.2
3.0
7.8
7.1
1.7
33.4
209.0
20 FBXO5 F-box protein 5 612020 ☆☆☆ 10.4 35.5
47.0
46.0
53.7
15.3
35.8
37.6
582.1
1344.1
21 SHCBP1 SHC SH2-domain binding protein 1 475347 ☆☆☆ 10.5 43.3
25.6
40.7
11.4
4.0
55.9
282.9
304.5
22 LOC485338 G2/mitotic-specific cyclin-B1 pseudogene 485338 12.0
23 CCNB2 cyclin B2 478324 ☆☆☆ 12.8 8.5
7.3
9.9
8.9
16.2
31.6
40.4
2183.9
24 CDC6 cell division cycle 6 480527 ☆☆☆ 13.2 37.5
30.4
56.2
20.9
54.8
16.8
1799.5
163.7
376.1
343.3
25 ATAD2 ATPase family, AAA domain containing 2 475090 ☆☆☆ 13.9 52.4
37.2
42.2
83.6
16.1
12.1
85.5
53.7
249.6
26 KIF23 kinesin family member 23 478355 ☆☆☆ 14.5 25.8
6.0
4.1
6.3
36.2
6.0
14.1
28.9
1559.6
22.3
9.0
26.5
27 MCM4 minichromosome maintenance complex component 4 477871 14.6 45.6
63.9
46.4
49.0
38.0
46.0
88.6
1186.9
61.5
84.0
40.6
28 C30H15orf23 chromosome 30 open reading frame, human C15orf23 478258 14.8
29 PLK4 polo-like kinase 4 476087 ☆☆☆ 15.5 53.4
28.0
26.0
27.8
85.7
31.9
26.8
448.4
1899.4
2784.3
30 RRM2 ribonucleotide reductase M2 482963 ☆☆☆ 16.5 15.9
17.1
33.3
6.0
8.1
14.1
15.6
860.5
197.6
222.0
656.8
31 KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 480469 ☆☆☆ 16.5 52.7
61.2
39.9
20.6
809.5
399.0
630.7
32 NEK2 NIMA-related kinase 2 480021 ☆☆☆ 16.6 12.1
27.0
62.6
55.3
34.2
36.2
27.1
1936.1
338.2
53.9
33 GTSE1 G-2 and S-phase expressed 1 608855 ☆☆☆ 17.2 48.1
83.1
28.9
15.0
150.9
40.2
78.0
54.7
1040.6
34 RACGAP1 Rac GTPase activating protein 1 486549 ☆☆☆ 17.3 10.9
9.2
37.7
34.9
16.8
19.8
2.8
28.5
51.4
151.9
88.0
14.2
35 SGOL1 shugoshin-like 1 (S. pombe) 610343 ☆☆☆ 17.6 129.6
32.6
999.2
5511.1
26.0
6.3
77.1
36 DEPDC1 DEP domain containing 1 479992 ☆☆☆ 17.9 28.6
34.6
17.1
4.9
57.4
12.7
5.7
97.9
1190.6
37 CDCA2 cell division cycle associated 2 477377 ☆☆☆ 19.3 53.0
33.2
26.5
9.0
62.2
26.4
21.0
1423.8
38 NDC80 NDC80 kinetochore complex component 480190 ☆☆☆ 19.8 22.7
14.1
4.6
35.8
14.1
30.3
50.5
1013.0
39 SPAG5 sperm associated antigen 5 480623 ☆☆☆ 20.2 29.2
35.7
25.3
44.9
73.1
13.1
110.4
40 TACC3 transforming, acidic coiled-coil containing protein 3 479079 ☆☆☆ 20.4 68.4
84.2
90.3
27.0
19.1
9.0
19.3
115.3
532.5
41 LOC476070 mitotic spindle assembly checkpoint protein MAD2A-like 476070 ☆☆☆ 21.2 17.1
52.1
41.4
22.3
22.2
49.7
53.7
61.8
729.3
164.9
273.1
457.9
42 KIAA0101 KIAA0101 ortholog 610710 ☆☆☆ 21.4 19.4
14.1
106.7
3.6
14.5
7.4
43 ORC6 origin recognition complex, subunit 6 482492 ☆☆☆ 22.6 97.0
102.6
338.0
134.9
191.4
172.6
465.6
2422.9
556.5
688.9
44 ORC1 origin recognition complex, subunit 1 475351 23.0
45 FAM54A family with sequence similarity 54, member A 483997 ☆☆☆ 23.0 65.0
102.0
95.0
160.2
105.3
439.8
1790.5
46 KNTC1 kinetochore associated 1 486254 ☆☆☆ 23.1 67.8
55.8
28.6
45.4
21.5
4.7
26.1
50.3
285.3
47 LOC488210 nudE nuclear distribution gene E homolog 1 (A. nidulans) pseudogene 488210 24.3
48 SPC25 SPC25, NDC80 kinetochore complex component 488388 ☆☆☆ 24.5 38.7
38.1
1065.5
8.3
22.3
33.6
3.7
523.7
49 CDC20 cell division cycle 20 homolog (S. cerevisiae) 482534 24.7
50 KIFC1 kinesin family member C1 607916 ☆☆☆ 25.0 76.0
41.7
27.9
25.0
15.9
66.7
82.2
6.4
4791.3
91.5
140.8
51 CKAP2L cytoskeleton associated protein 2-like 475753 ☆☆☆ 25.3 48.4
22.3
8.1
28.5
3.9
1053.3
52 PTTG1 pituitary tumor-transforming 1 479307 ☆☆☆ 25.8 30.6
17.0
43.9
13.6
353.3
2578.7
30.0
34.9
53 PBK PDZ binding kinase 477371 ☆☆☆ 26.0 11.3
21.8
8.5
2904.4
2.2
7.5
5.1
12.1
198.3
158.8
54 HELLS helicase, lymphoid-specific 486809 ☆☆☆ 26.1 74.0
53.4
25.9
14.8
29.1
37.5
55 KIF4A kinesin family member 4A 491941 ☆☆☆ 26.4 10.2
11.4
26.8
6.0
62.7
18.1
13.9
9.4
147.1
167.3
459.5
50.8
56 MCM3 minichromosome maintenance complex component 3 481839 ☆☆☆ 26.8 106.8
121.0
56.9
19.4
732.9
17.6
58.8
33.5
110.0
130.9
104.2
57 STIL SCL/TAL1 interrupting locus 610305 ☆☆☆ 27.9 45.9
43.5
88.6
25.1
32.9
13.4
159.2
1664.9
58 AURKA aurora kinase A 485940 ☆☆☆ 29.0 26.8
24.4
42.4
30.0
31.1
43.8
20.5
30.0
943.5
532.8
749.0
126.5
59 MIS18A MIS18 kinetochore protein homolog A (S. pombe) 609701 ☆☆☆ 29.8 108.4
174.5
141.7
711.7
53.5
94.4
37.4
160.5
431.6
60 FANCD2 Fanconi anemia, complementation group D2 484659 ☆☆☆ 29.9 64.0
54.4
75.6
51.8
139.3
31.6
32.5
1850.7
74.6
223.9
61 LOC479820 exonuclease NEF-sp 479820 ☆☆☆ 30.3 148.8
161.1
182.9
550.5
546.9
270.1
1065.8
62 PRC1 protein regulator of cytokinesis 1 488742 ☆☆☆ 31.4 13.6
3.7
19.2
4.9
9.5
4.2
1.7
475.7
63 CDCA3 cell division cycle associated 3 611617 ☆☆☆ 31.8 25.4
95.9
39.7
17.2
8.8
19.0
9.9
16.2
64 ECT2 epithelial cell transforming sequence 2 oncogene 488172 ☆☆☆ 32.5 30.2
19.3
39.5
63.6
11.6
4.9
6.3
81.3
1443.6
144.8
14.4
149.2
65 CENPF centromere protein F, 350/400kDa (mitosin) 610263 32.7
66 CENPA centromere protein A 475692 ☆☆☆ 32.8 14.0
80.2
67.5
54.4
28.2
44.2
341.7
67 PLK1 polo-like kinase 1 489971 ☆☆☆ 32.9 95.4
30.7
41.7
39.0
46.1
16.1
5.8
900.8
68.2
97.3
1551.8
123.0
68 ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 486098 ☆☆☆ 33.2 156.8
44.9
73.3
44.0
7.5
14.0
235.8
1146.3
69 MCM2 minichromosome maintenance complex component 2 484622 33.7 66.8
164.9
101.5
46.0
40.2
53.3
97.9
48.7
1292.7
48.8
78.2
22.4
70 SKA3 spindle and kinetochore associated complex subunit 3 609400 ☆☆☆ 33.7 78.8
40.3
20.9
85.0
74.3
29.7
65.7
71 NCAPD2 non-SMC condensin I complex, subunit D2 477715 ☆☆☆ 35.1 52.1
33.0
45.5
18.3
9.3
24.2
26.6
21.0
23.9
1913.5
72 EZH2 enhancer of zeste homolog 2 (Drosophila) 475511 ☆☆☆ 35.3 50.8
37.1
27.7
18.9
24.8
36.2
126.0
1516.5
252.0
557.0
73 CEP55 centrosomal protein 55kDa 477773 ☆☆☆ 35.7 9.8
11.8
6.2
7.8
11.6
162.0
982.9
74 CENPH centromere protein H 610124 ☆☆☆ 36.1 90.5
190.2
93.0
192.5
65.1
30.4
41.0
75 MCM6 minichromosome maintenance complex component 6 476131 ☆☆☆ 36.2 58.6
90.1
60.2
22.0
14.4
44.2
59.0
18.5
28.0
56.7
76 PRIM2 primase, DNA, polypeptide 2 (58kDa) 474950 ☆☆☆ 36.6 519.2
184.4
100.8
65.3
91.9
224.5
1042.3
293.3
58.9
77 MCM5 minichromosome maintenance complex component 5 610519 ☆☆☆ 37.0 158.1
156.1
236.8
65.6
10.9
41.8
54.5
27.9
1376.6
83.4
86.3
80.0
78 NCAPD3 non-SMC condensin II complex, subunit D3 489270 38.3
79 RRM1 ribonucleotide reductase M1 476823 ☆☆☆ 38.6 73.8
51.0
83.3
139.7
12.2
12.0
29.9
1031.2
115.3
126.0
20.4
80 FOXM1 forkhead box M1 486743 ☆☆☆ 39.3 44.3
33.6
34.1
18.0
93.8
38.2
13.5
35.5
1352.7
81 MLF1IP MLF1 interacting protein 607799 ☆☆☆ 40.9 31.4
45.2
37.6
27.9
135.8
127.9
56.1
228.2
82 CHEK1 checkpoint kinase 1 609767 ☆☆☆ 41.4 67.3
36.9
72.9
7.3
66.7
82.4
89.4
615.0
905.8
103.9
88.6
103.2
83 CENPK centromere protein K 609707 ☆☆☆ 42.1 25.1
38.3
21.0
25.9
24.5
53.8
32.3
121.0
1259.9
84 POLA2 polymerase (DNA directed), alpha 2, accessory subunit 476025 ☆☆☆ 43.1 174.1
178.4
264.1
135.0
155.6
108.4
243.0
736.9
704.4
305.0
85 KIF18A kinesin family member 18A 485426 ☆☆☆ 43.6 60.4
31.0
18.0
29.4
88.4
84.6
90.5
804.4
86 CENPT centromere protein T 611127 ☆☆☆ 43.9 8050.6
11525.2
17181.0
512.6
113.2
216.9
35.9
43.5
87 DNMT1 DNA (cytosine-5-)-methyltransferase 1 476715 ☆☆☆ 45.0 103.2
143.2
225.6
15305.9
62.7
91.0
144.2
7566.8
1462.6
88 KIF20B kinesin family member 20B 477761 ☆☆☆ 45.2 71.7
56.4
39.2
67.2
38.9
15.5
7.5
694.4
89 NCAPG2 non-SMC condensin II complex, subunit G2 475559 ☆☆☆ 46.3 38.2
30.2
36.7
85.5
22.3
18.6
50.0
90 RAD51 RAD51 homolog (S. cerevisiae) 403568 ☆☆☆ 46.7 62.6
96.0
81.2
14.0
18.6
27.9
23.9
91.7
361.3
1542.8
1359.5
1855.5
91 CDT1 chromatin licensing and DNA replication factor 1 479616 ☆☆☆ 47.2 141.3
267.5
189.5
63.7
168.2
155.7
48.0
2086.9
92 GSG2 germ cell associated 2 (haspin) 611109 ☆☆☆ 47.4 208.9
169.4
123.4
40.0
90.1
90.7
73.3
25.0
93 ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 607879 ☆☆☆ 47.9 57.4
119.2
27.2
30.6
26.3
7.1
94 TK1 thymidine kinase 1, soluble 483343 48.3
95 CENPN centromere protein N 479635 ☆☆☆ 49.2 89.5
81.5
308.4
14.3
50.9
76.4
51.2
54.8
96 BIRC5 baculoviral IAP repeat containing 5 442936 ☆☆☆ 50.2 14.1
68.5
10.6
2.5
40.0
29.1
41.4
697.2
600.0
97 DIAPH3 diaphanous-related formin 3 485474 ☆☆☆ 51.6 37.8
37.5
11.2
34.2
136.3
26.1
21.4
98 DSN1 DSN1, MIS12 kinetochore complex component 610279 ☆☆☆ 51.6 140.4
117.3
87.9
1354.0
90.2
89.7
50.0
346.7
99 SPC24 SPC24, NDC80 kinetochore complex component 611174 ☆☆☆ 51.8 80.9
134.5
160.4
2247.6
42.1
99.3
33.2
821.2
100 WHSC1 Wolf-Hirschhorn syndrome candidate 1 479077 ☆☆☆ 51.9 65.0
101.7
143.0
50.9
55.2
369.1
94.6
2172.2
1805.8
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