COXPRESdb

ver. 6.0



Rno: Top2a External Links; ncbi pubmed
Orthologous gene group in HomoloGene**
Hsa genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Hsa2 genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Hsa3 genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Mcc genes
TOP2A ☆☆☆ DNA topoisomerase 2-alpha-like
Mmu genes
Top2a ☆☆☆ topoisomerase (DNA) II alpha
Mmu2 genes
Top2a ☆☆☆ topoisomerase (DNA) II alpha
Cfa genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Gga genes
TOP2A ☆☆☆ topoisomerase (DNA) II alpha 170kDa
Dre genes
top2a topoisomerase (DNA) II alpha
Dme genes
Top2 ☆☆☆ Topoisomerase 2
Dme2 genes
Top2 Topoisomerase 2
Cel genes
top-2 ☆☆ Protein TOP-2


Top 100 coexpressed genes to Top2a (Rno c3.0 coexpression data)

KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04110 Cell cycle 14
rno04114 Oocyte meiosis 10
rno04914 Progesterone-mediated oocyte maturation 6
rno04115 p53 signaling pathway 4
rno00240 Pyrimidine metabolism 3

Row filter: Column filter:
  Gene Function KEGG Entrez Gene ID Supportability* Rno
Rno MR*
for
Top2a
 
Link Hsa
Hsa MR*
for
TOP2A
[list]
☆☆☆
Hsa2
Hsa2 MR*
for
TOP2A
[list]
☆☆☆
Hsa3
Hsa3 MR*
for
TOP2A
[list]
☆☆☆
Mcc
Mcc MR*
for
TOP2A
[list]
☆☆☆
Mmu
Mmu MR*
for
Top2a
[list]
☆☆☆
Mmu2
Mmu2 MR*
for
Top2a
[list]
☆☆☆
Cfa
Cfa MR*
for
TOP2A
[list]
☆☆☆
Gga
Gga MR*
for
TOP2A
[list]
☆☆☆
Dre
Dre MR*
for
top2a
[list]
 
Dme
Dme MR*
for
Top2
[list]
☆☆☆
Dme2
Dme2 MR*
for
Top2
[list]
 
Cel
Cel MR*
for
top-2
[list]
☆☆
0 Top2a topoisomerase (DNA) II alpha 360243 ☆☆☆ 0.0 0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
1 Nusap1 nucleolar and spindle associated protein 1 311336 ☆☆☆ 1.7 4.6
3.2
3.0
7.8
7.1
10.2
33.4
209.0
2 Mki67 marker of proliferation Ki-67 291234 ☆☆☆ 2.0 32.1
2.6
1.0
10.5
1.7
1.0
3 Racgap1 Rac GTPase-activating protein 1 315298 ☆☆☆ 2.8 10.9
9.2
37.7
34.9
16.8
19.8
17.3
28.5
51.4
151.9
88.0
14.2
4 Spc25 SPC25, NDC80 kinetochore complex component 295661 ☆☆☆ 3.7 38.7
38.1
1065.5
8.3
22.3
33.6
24.5
523.7
5 Prc1 protein regulator of cytokinesis 1 308761 ☆☆☆ 4.2 13.6
3.7
19.2
4.9
9.5
31.4
1.7
475.7
6 Ttk Ttk protein kinase 315852 ☆☆☆ 4.8 12.7
16.0
8.1
34.6
14.9
3.0
91.6
337.4
7 Pbk PDZ binding kinase 290326 ☆☆☆ 5.1 11.3
21.8
8.5
2904.4
2.2
7.5
26.0
12.1
198.3
158.8
8 Depdc1 DEP domain containing 1 295538 ☆☆☆ 5.7 28.6
34.6
17.1
4.9
57.4
12.7
17.9
97.9
1190.6
9 Cdk1 cyclin-dependent kinase 1 54237 ☆☆☆ 5.7 1.4
12.1
3.3
3.5
1.0
2.0
24.7
543.8
76.5
177.8
760.3
10 Ect2 epithelial cell transforming 2 361921 6.3 30.2
19.3
39.5
63.6
11.6
4.9
32.5
81.3
1443.6
144.8
14.4
149.2
11 Kifc1 kinesin family member C1 294286 ☆☆☆ 6.4 76.0
41.7
27.9
25.0
15.9
66.7
82.2
25.0
4791.3
91.5
140.8
12 Kif18b kinesin family member 18B 303575 ☆☆☆ 6.9 8.1
174.9
456.8
68.1
15.9
1121.4
111.2
13 Espl1 extra spindle pole bodies homolog 1 (S. cerevisiae) 315330 ☆☆☆ 7.1 57.4
119.2
27.2
30.6
26.3
47.9
14 Ns5atp9 NS5A (hepatitis C virus) transactivated protein 9 300795 ☆☆☆ 7.4 19.4
14.1
106.7
3.6
14.5
21.4
15 Kif20b kinesin family member 20B 309523 ☆☆☆ 7.5 71.7
56.4
39.2
67.2
38.9
15.5
45.2
694.4
16 Ube2c ubiquitin-conjugating enzyme E2C 296368 ☆☆☆ 7.8 12.7
52.8
18.2
4.5
13.1
31.7
96.5
1009.5
1389.4
17 LOC687121 similar to Shc SH2-domain binding protein 1 687121 8.7
18 Ncaph non-SMC condensin I complex, subunit H 680089 8.7
19 Ccna2 cyclin A2 114494 ☆☆☆ 8.9 29.1
10.9
18.7
6.3
3.5
17.8
7.0
59.6
1472.3
103.8
29.8
20 Bub1 BUB1 mitotic checkpoint serine/threonine kinase 296137 ☆☆☆ 9.8 8.0
4.0
4.2
4.6
1.4
46.3
21 Cdca3 cell division cycle associated 3 297594 ☆☆☆ 9.9 25.4
95.9
39.7
17.2
8.8
19.0
31.8
16.2
22 Bub1b BUB1 mitotic checkpoint serine/threonine kinase B 171576 ☆☆☆ 10.1 7.3
8.8
4.6
16.2
6.8
3.9
10.0
274.2
23 Iqgap3 IQ motif containing GTPase activating protein 3 310621 ☆☆☆ 10.4 35.0
67.9
17.0
17.2
63.0
24.2
1802.5
12730.7
24 Ube2t ubiquitin-conjugating enzyme E2T (putative) 360847 ☆☆☆ 10.9 27.5
38.6
97.8
53.2
61.0
105.9
73.6
97.9
1117.2
25 Ska1 spindle and kinetochore associated complex subunit 1 291441 ☆☆☆ 10.9 108.8
83.7
1597.5
46.9
28.2
406.6
1634.4
26 Aurkb aurora kinase B 114592 ☆☆☆ 10.9 44.0
88.9
27.1
49.1
12.7
9.8
82.2
27 Nuf2 NUF2, NDC80 kinetochore complex component 304951 ☆☆☆ 12.0 9.4
8.8
13.5
3.0
17.9
44.9
9.9
41.8
459.1
28 Cenpi centromere protein I 25448 ☆☆☆ 12.2 106.0
28.6
42.9
69.7
22.6
62.2
46.4
29 Kif11 kinesin family member 11 171304 ☆☆☆ 13.0 2.8
1.4
6.0
18.7
2.5
1.0
27.6
792.6
26.9
22.4
30 Arhgap11a Rho GTPase activating protein 11A 296060 ☆☆☆ 13.0 125.9
12.0
58.6
11.6
21.1
9.8
69.2
1568.2
31 Spag5 sperm associated antigen 5 252918 ☆☆☆ 13.1 29.2
35.7
25.3
44.9
73.1
20.2
110.4
32 Kif2c kinesin family member 2C 171529 ☆☆☆ 13.2 26.9
45.4
8.7
9.5
19.4
14.3
173.0
47.4
155.8
33 Hmmr hyaluronan mediated motility receptor (RHAMM) 25460 ☆☆☆ 13.3 5.3
21.6
6.0
41.0
71.8
90.9
232.4
34 Foxm1 forkhead box M1 58921 ☆☆☆ 13.5 44.3
33.6
34.1
18.0
93.8
38.2
39.3
35.5
1352.7
35 Kif4a kinesin family member 4A 84393 ☆☆☆ 13.9 10.2
11.4
26.8
6.0
62.7
18.1
26.4
9.4
147.1
167.3
459.5
50.8
36 Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 691979 ☆☆☆ 14.0 156.8
44.9
73.3
44.0
7.5
33.2
235.8
1146.3
37 Kif23 kinesin family member 23 315740 ☆☆☆ 14.1 25.8
6.0
4.1
6.3
36.2
6.0
14.5
28.9
1559.6
22.3
9.0
26.5
38 Rrm2 ribonucleotide reductase M2 362720 ☆☆☆ 14.1 15.9
17.1
33.3
6.0
8.1
16.5
15.6
860.5
197.6
222.0
656.8
39 Aspm asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 289054 ☆☆☆ 14.1 1.4
3.0
1.7
18.6
19.1
3.0
2.8
165.7
40 Ckap2 cytoskeleton associated protein 2 306575 ☆☆☆ 15.5 34.9
13.5
39.0
9.2
25.0
10.8
8.4
56.2
1680.2
41 Plk1 polo-like kinase 1 25515 ☆☆☆ 16.1 95.4
30.7
41.7
39.0
46.1
32.9
5.8
900.8
68.2
97.3
1551.8
123.0
42 Ccnb1 cyclin B1 25203 ☆☆☆ 17.0 12.7
11.6
28.0
8.9
6.5
3.0
15.0
1579.0
139.6
69.3
43 Ccnf cyclin F 117524 ☆☆☆ 17.1 99.0
145.5
90.9
56.5
76.5
60.2
62.0
133.6
948.5
44 Dlgap5 discs, large (Drosophila) homolog-associated protein 5 289997 ☆☆☆ 18.0 4.6
1.0
3.9
7.1
62.6
16.9
6.5
54.5
97.3
45 Kif22 kinesin family member 22 293502 ☆☆☆ 18.0 153.1
106.9
235.1
97.8
20.4
36.7
77.4
46 Anlnl1 anillin, actin binding protein-like 1 307056 18.2
47 Asf1b anti-silencing function 1B histone chaperone 304648 ☆☆☆ 18.3 62.8
97.3
58.3
36.5
27.4
41.0
52.0
48 Kif20a kinesin family member 20A 361308 ☆☆☆ 18.5 9.5
11.5
2.8
27.1
17.4
19.0
8368.5
49 Tacc3 transforming, acidic coiled-coil containing protein 3 360962 ☆☆☆ 19.3 68.4
84.2
90.3
27.0
19.1
9.0
20.4
115.3
532.5
50 Aurka aurora kinase A 261730 ☆☆☆ 20.5 26.8
24.4
42.4
30.0
31.1
43.8
29.0
30.0
943.5
532.8
749.0
126.5
51 Cdca2 cell division cycle associated 2 305984 ☆☆☆ 21.0 53.0
33.2
26.5
9.0
62.2
26.4
19.3
1423.8
52 Diaph3 diaphanous-related formin 3 290396 ☆☆☆ 21.4 37.8
37.5
11.2
34.2
136.3
26.1
51.6
53 E2f8 E2F transcription factor 8 308607 ☆☆☆ 21.6 41.2
119.1
46.3
13.1
63.3
24.2
58.6
74.2
1341.4
54 Tubb5 tubulin, beta 5 class I 29214 ☆☆☆ 22.1 217.2
279.4
2193.9
64.0
118.6
58.3
3279.7
1500.1
283.2
135.2
44.1
55 Depdc1b DEP domain containing 1B 310074 ☆☆☆ 22.8 34.6
32.5
23.8
93.2
36.1
6.0
160.0
56 Cdc20 cell division cycle 20 64515 ☆☆☆ 22.8 24.9
56.1
35.3
12.4
24.4
8.2
961.9
119.7
64.3
57 Cenpe centromere protein E 362044 ☆☆☆ 23.4 24.8
27.9
8.9
18.8
21.0
3.7
40.0
58 Cdca8 cell division cycle associated 8 500545 ☆☆☆ 23.7 51.0
84.0
21.2
9.2
6.0
19.9
86.2
103.2
888.6
59 Rad51 RAD51 recombinase 499870 ☆☆☆ 23.9 62.6
96.0
81.2
14.0
18.6
27.9
46.7
91.7
361.3
1542.8
1359.5
1855.5
60 Ncapd2 non-SMC condensin I complex, subunit D2 362438 ☆☆☆ 24.2 52.1
33.0
45.5
18.3
9.3
35.1
26.6
21.0
23.9
1913.5
61 Melk maternal embryonic leucine zipper kinase 362510 ☆☆☆ 24.2 17.7
9.8
44.9
3.2
12.1
11.3
80.6
60.4
72.9
72.4
62 Knstrn kinetochore-localized astrin/SPAG5 binding protein 311325 ☆☆☆ 24.7 78.5
96.0
88.5
47.7
53.2
63 Pole polymerase (DNA directed), epsilon, catalytic subunit 304573 24.8 413.0
183.4
276.7
29.9
20.6
52.2
225.1
147.8
97.5
50.2
64 Hmgb2 high mobility group box 2 29395 ☆☆☆ 26.0 1507.1
65 Kntc1 kinetochore associated 1 304477 ☆☆☆ 26.1 67.8
55.8
28.6
45.4
21.5
4.7
23.1
50.3
285.3
66 Fam83d family with sequence similarity 83, member D 311598 ☆☆☆ 26.6 49.4
114.6
49.4
135.7
57.0
8435.4
1.0
481.5
67 Suv39h1 suppressor of variegation 3-9 homolog 1 (Drosophila) 302553 ☆☆☆ 26.6 240.9
285.1
961.6
343.9
101.7
172.8
180.9
68 Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 54238 ☆☆☆ 26.8 83.7
168.9
2903.3
328.4
288.4
480.5
110.8
5376.0
69 Tcf19 transcription factor 19 406195 ☆☆☆ 28.9 81.8
94.7
28.4
76.6
178.1
70 Birc5 baculoviral IAP repeat-containing 5 64041 29.1 14.1
68.5
10.6
2.5
40.0
50.2
41.4
697.2
600.0
71 Uhrf1 ubiquitin-like with PHD and ring finger domains 1 316129 ☆☆☆ 29.2 28.8
179.0
59.8
9.8
8.8
7.1
91.4
6.0
567.9
72 Ska3 spindle and kinetochore associated complex subunit 3 361047 ☆☆☆ 29.7 78.8
40.3
20.9
85.0
74.3
33.7
65.7
73 Cenpq centromere protein Q 363198 ☆☆☆ 29.9 147.1
234.1
238.1
47.8
252.5
80.5
113.7
74 Pttg1 pituitary tumor-transforming 1 64193 ☆☆☆ 30.0 30.6
17.0
43.9
13.6
353.3
2578.7
25.8
34.9
75 Ndc80 NDC80 kinetochore complex component 301701 ☆☆☆ 30.3 22.7
14.1
4.6
35.8
14.1
19.8
50.5
1013.0
76 Tk1 thymidine kinase 1, soluble 24834 30.6 57.2
121.2
78.7
105.6
29.0
59.2
27.9
151.6
3363.9
77 Ccnb2 cyclin B2 363088 ☆☆☆ 31.6 8.5
7.3
9.9
8.9
16.2
12.8
40.4
2183.9
78 Clspn claspin 298534 ☆☆☆ 31.6 1729.4
74.4
403.1
1239.5
36.0
13.3
101.7
247.9
249.5
61.9
867.1
79 Cenpw centromere protein W 689399 ☆☆☆ 31.8 60.7
78.8
79.5
19.2
62.3
129.9
55.4
80 Plk4 polo-like kinase 4 310344 ☆☆☆ 31.9 53.4
28.0
26.0
27.8
85.7
15.5
26.8
448.4
1899.4
2784.3
81 Smc2 structural maintenance of chromosomes 2 362519 ☆☆☆ 32.0 32.6
49.0
48.0
12.7
5.5
7.3
196.6
16.1
8.1
2.6
5.9
82 Cenpk centromere protein K 294712 ☆☆☆ 32.3 25.1
38.3
21.0
25.9
24.5
53.8
42.1
121.0
1259.9
83 Fancd2 Fanconi anemia, complementation group D2 312641 ☆☆☆ 32.5 64.0
54.4
75.6
51.8
139.3
31.6
29.9
1850.7
74.6
223.9
84 Spc24 SPC24, NDC80 kinetochore complex component 363028 33.2 80.9
134.5
160.4
2247.6
42.1
99.3
51.8
821.2
85 Smc4 structural maintenance of chromosomes 4 295107 ☆☆☆ 33.3 45.5
35.7
21.2
34.9
13.9
14.1
59.9
35.6
697.6
14.5
1.0
86 Cenpt centromere protein T 307805 ☆☆☆ 35.9 8050.6
11525.2
17181.0
512.6
113.2
216.9
43.9
43.5
87 Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit 312299 ☆☆☆ 36.2 50.8
37.1
27.7
18.9
24.8
35.3
126.0
1516.5
252.0
557.0
88 Rbl1 retinoblastoma-like 1 (p107) 680111 ☆☆☆ 36.4 108.0
99.8
427.4
2091.3
16.8
79.2
75.7
88.8
1092.6
443.7
89 Mis18a MIS18 kinetochore protein A 288272 ☆☆☆ 37.4 108.4
174.5
141.7
711.7
53.5
94.4
29.8
160.5
431.6
90 Fbxo5 F-box protein 5 292263 ☆☆☆ 37.6 35.5
47.0
46.0
53.7
15.3
35.8
10.4
582.1
1344.1
91 Trip13 thyroid hormone receptor interactor 13 292206 ☆☆☆ 38.1 44.8
61.3
82.4
26.6
21.7
17.2
77.2
111.2
847.0
227.3
522.4
1803.4
92 Rrm1-ps1 ribonucleotide reductase M1, pseudogene 1 365320 38.6
93 LOC500700 similar to chromosome 14 open reading frame 145 500700 39.6
94 Kpna2 karyopherin alpha 2 85245 ☆☆☆ 39.9 52.7
61.2
16.5
20.6
809.5
399.0
630.7
95 Trim59 tripartite motif-containing 59 365813 ☆☆☆ 40.0 112.2
99.9
294.7
51.6
53.9
89.4
96 Ncapd3 non-SMC condensin II complex, subunit D3 315508 ☆☆☆ 40.1 94.4
111.6
140.7
326.4
142.1
182.7
92.8
797.9
97 Mms22l MMS22-like, DNA repair protein 313108 ☆☆☆ 40.2 123.0
429.7
70.2
25.1
162.8
189.5
1128.8
98 Kif15 kinesin family member 15 353302 ☆☆☆ 41.8 17.0
25.8
9.6
4438.3
9.6
8.2
29.7
104.9
99 Ddx11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 316767 ☆☆☆ 43.5 481.7
596.9
398.5
665.0
218.2
103.7
1642.7
1709.4
1558.5
413.8
210.0
2355.2
100 Mcm6 minichromosome maintenance complex component 6 29685 ☆☆☆ 44.2 58.6
90.1
60.2
22.0
14.4
36.2
59.0
18.5
28.0
56.7
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